Animal models are widely used to develop drugs for treating diabetes mellitus (DM). Insulin
resistance (IR) is one of the main problems in type-2 DM (T2DM). Streptozotocin (STZ) is …

Abstract Purpose of Review Since the mid-twentieth century, obesity and its related
comorbidities, notably insulin resistance (IR) and type 2 diabetes (T2D), have surged …

Background This study evaluated the antihyperglycemic, anti–bone‐resorptive, and anti‐
inflammatory efficacy of the probiotic Lactobacillus rhamnosus EM1107 in an experimental …

Background: Ocimum gratissimum (OG) is used in the traditional management of diabetes in
Nigeria. This study investigated the anti-diabetic potential of OG leaf fractions (OGLF) in a rat …

Quercetin, a flavonoid found in fruits and vegetables, is widely distributed as a secondary
metabolite in the plant kingdom. Oxidative stress plays a role in the pathogenesis of …

Porous poly (lactic-co-glycolic acid)(PLGA) microspheres were prepared, loaded with
insulin, and then coated in poly (vinyl alcohol)(PVA) and a novel boronic acid-containing …

The development of a stable disease model with an adequate biochemical profile is crucial
for the preclinical investigation of new antidiabetic agents. This study aimed at optimization …

The prevalence of cardiovascular disease among type-2 diabetic patients has become a
source of major concern world over. This study explored the protective effect of kolaviron, a …

Background: Vernonia amygdalina (VA) is used in the traditional management of diabetes in
Nigeria. Previous scientific verification of VA is on Type-1 diabetes model, in spite of the …

Objectives Diabetic nephropathy (DN) is one of the most important complications of diabetes
mellitus and it is considered as a principal cause for end-stage renal failure. Ganoderma …