[HTML][HTML] Enterovirus A71 antivirals: past, present, and future
Abstract Enterovirus A71 (EV-A71) is a significant human pathogen, especially in children.
EV-A71 infection is one of the leading causes of hand, foot, and mouth diseases (HFMD) …
EV-A71 infection is one of the leading causes of hand, foot, and mouth diseases (HFMD) …
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
C Ma, MD Sacco, B Hurst, JA Townsend, Y Hu, T Szeto… - Cell research, 2020 - nature.com
A new coronavirus SARS-CoV-2, also called novel coronavirus 2019 (2019-nCoV), started
to circulate among humans around December 2019, and it is now widespread as a global …
to circulate among humans around December 2019, and it is now widespread as a global …
[HTML][HTML] Advances in anti-EV-A71 drug development research
Abstract Background Enterovirus A71 (EV-A71) is capable of causing hand, foot and mouth
disease (HFMD), which may lead to neurological sequelae and even death. As EV-A71 is …
disease (HFMD), which may lead to neurological sequelae and even death. As EV-A71 is …
Enteroviral proteases: structure, host interactions and pathogenicity
OH Laitinen, E Svedin, S Kapell… - Reviews in medical …, 2016 - Wiley Online Library
Enteroviruses are common human pathogens, and infections are particularly frequent in
children. Severe infections can lead to a variety of diseases, including poliomyelitis, aseptic …
children. Severe infections can lead to a variety of diseases, including poliomyelitis, aseptic …
Insight into the Enterovirus A71: A review
Enterovirus A71 is a major causative pathogen of hand, foot and mouth disease. It has
become a global public health threat, and is especially important for infants and young …
become a global public health threat, and is especially important for infants and young …
Enterovirus D68 antivirals: past, present, and future
Y Hu, R Musharrafieh, M Zheng… - ACS infectious diseases, 2020 - ACS Publications
Enterovirus D68 (EV-D68) is an RNA virus that causes respiratory illnesses mainly in
children. In severe cases, it can lead to neurological complications such as acute flaccid …
children. In severe cases, it can lead to neurological complications such as acute flaccid …
Picornavirus 2A protease regulates stress granule formation to facilitate viral translation
Stress granules (SGs) contain stalled messenger ribonucleoprotein complexes and are
related to the regulation of mRNA translation. Picornavirus infection can interfere with the …
related to the regulation of mRNA translation. Picornavirus infection can interfere with the …
Innate immunity and immune evasion by enterovirus 71
Enterovirus 71 (EV71) is a major infectious disease affecting millions of people worldwide
and it is the main etiological agent for outbreaks of hand foot and mouth disease (HFMD) …
and it is the main etiological agent for outbreaks of hand foot and mouth disease (HFMD) …
Validating Enterovirus D68-2Apro as an Antiviral Drug Target and the Discovery of Telaprevir as a Potent D68-2Apro Inhibitor
ABSTRACT Enterovirus D68 (EV-D68) is a viral pathogen that leads to severe respiratory
illness and has been linked with the development of acute flaccid myelitis (AFM) in children …
illness and has been linked with the development of acute flaccid myelitis (AFM) in children …
[HTML][HTML] Update on enteroviral protease 2A: Structure, function, and host factor interaction
Y Liu, J Li, Y Zhang - Biosafety and Health, 2023 - Elsevier
Enteroviruses (EVs) are human pathogens commonly observed in children aged 0–5 years
and adults. EV infections usually cause the common cold and hand-foot-and-mouth disease; …
and adults. EV infections usually cause the common cold and hand-foot-and-mouth disease; …