The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance
In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …
around the globe. Although it is twenty nucleotides long, it can modulate several gene …
Biological factors underlying sex differences in neurological disorders
The prevalence, age of onset, pathophysiology, and symptomatology of many neurological
and neuropsychiatric conditions differ significantly between males and females. Females …
and neuropsychiatric conditions differ significantly between males and females. Females …
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
To identify genetic factors contributing to type 2 diabetes (T2D), we performed large-scale
meta-analyses by using a custom∼ 50,000 SNP genotyping array (the ITMAT-Broad-CARe …
meta-analyses by using a custom∼ 50,000 SNP genotyping array (the ITMAT-Broad-CARe …
Circulating microRNAs involved in multiple sclerosis
Multiple sclerosis (MS) is an immune-mediated, demyelinating and neurodegenerative
disease of the central nervous system. After traumatic brain injury, it is the leading cause of …
disease of the central nervous system. After traumatic brain injury, it is the leading cause of …
The human testis‐determining factor SRY localizes in midbrain dopamine neurons and regulates multiple components of catecholamine synthesis and metabolism
J. Neurochem.(2012) 122, 260–271. Abstract The male gender is determined by the sex‐
determining region on the Y chromosome (SRY) transcription factor. The unexpected action …
determining region on the Y chromosome (SRY) transcription factor. The unexpected action …
The blood-brain barrier in multiple sclerosis: microRNAs as key regulators
W W. Kamphuis, C Derada Troletti… - CNS & Neurological …, 2015 - benthamdirect.com
Multiple sclerosis (MS) is a progressive inflammatory disease of the central nervous system
(CNS) leading to severe neurological deficits. To date, no treatment is available that halts …
(CNS) leading to severe neurological deficits. To date, no treatment is available that halts …
Sry, more than testis determination?
ME Turner, D Ely, J Prokop… - American Journal of …, 2011 - journals.physiology.org
The Sry locus on the mammalian Y chromosome is the developmental switch responsible for
testis determination. Inconsistent with this important function, the Sry locus is transcribed in …
testis determination. Inconsistent with this important function, the Sry locus is transcribed in …
[PDF][PDF] The male fight‐flight response: A result of SRY regulation of catecholamines?
Evidence from clinical and basic research studies support this hypothesis, as males exhibit
heightened sympathetic reactivity to stress that is associated with elevated cardiovascular …
heightened sympathetic reactivity to stress that is associated with elevated cardiovascular …
Disorders of blood pressure regulation—role of catecholamine biosynthesis, release, and metabolism
G Currie, EM Freel, CG Perry… - Current hypertension …, 2012 - Springer
Catecholamines (epinephrine and norepinephrine) are synthesised and produced by the
adrenal medulla and postganglionic nerve fibres of the sympathetic nervous system. It is …
adrenal medulla and postganglionic nerve fibres of the sympathetic nervous system. It is …
The Autosomal Short Tandem Repeat Polymorphisms Are Potentially Associated with Cardiovascular Disease Predisposition in the Latin American Population: A Mini …
AK Zambrano, S Cadena-Ullauri… - BioMed Research …, 2023 - Wiley Online Library
According to the World Health Organization, cardiovascular diseases (CVDs) are the
leading cause of death worldwide across nearly all ethnic groups. Inherited cardiac …
leading cause of death worldwide across nearly all ethnic groups. Inherited cardiac …