Spinal cord injury (SCI) and spinal cord tumor are devastating events causing structural and
functional impairment of the spinal cord and resulting in high morbidity and mortality; these …

IL-1, plays a role in some pathological inflammatory conditions. This pro-inflammatory
cytokine also has a crucial role in tumorigenesis and immune responses in the tumor …

Pancreatic cancer, one of the most prevalent tumors of the digestive system, has a dismal
prognosis. Cancer of the pancreas is distinguished by an inflammatory tumor …

The interleukin-1 receptor antagonist (IL-1Ra) is an anti-inflammatory cytokine and a
naturally occurring antagonist of the IL-1 receptor. It effectively counteracts the IL-1 signaling …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with
a few curative options. Desmoplastic stroma and immune system evasion in PDAC …

The tumor microenvironment (TME) is crucial to neoplastic processes, fostering proliferation,
angiogenesis and metastasis. Epigenetic regulations, primarily including DNA and RNA …

Introduction Pancreatic Ductal Adenocarcinoma (PDA) is one of the most aggressive
malignancies with a 5-year survival rate of 13%. Less than 20% of patients have a …

Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive form of cancer with a
low survival rate. A successful treatment strategy should not be limited to targeting cancer …

Purpose This review article summarizes the pathophysiological aspects of interleukins (ILs)
including IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, and IL-10 in pancreatic cancer (PC) …

Simple Summary Sex is a factor that affects how the immune system works in both healthy
and sick people. There are differences between females and males in various aspects of …