Solomonamides, a pair of macrocyclic peptide natural products originating from marine
sources, have garnered significant attention within the synthetic community owing to their …

The total synthesis of a potent multi-drug-resistant reverser, dysoxylacatam A (1), was
achieved in a highly efficient and stereocontrolled fashion. The highlights of the strategy …

This is a review of papers published in the year 2018 that focus on the synthesis, reactivity,
or properties of compounds containing a carbon-transition metal double or triple bond …

A photoinduced reductive Reformatsky reaction by cooperative dual-metal catalysis is
described. This methodology enables the implementation of this venerable reaction in …

Cyclopeptides are ubiquitous scaffolds and could exert the anticancer effects through
diverse mechanisms, inclusive of induction of apoptosis and autophagy, antiangiogenesis …

A synthetic strategy based on the application of three consecutive ring-expansion reactions
has been used in the synthesis of analogues of the macrocyclic core of the solomonamide …

Herein, we report the total synthesis of solomonamide A along with its structural revision for
the first time. The natural product possesses very potent anti-inflammatory activity, and it …

Marine sponges are a prolific source of bioactive compounds. In this work, the putative
antiangiogenic potential of a series of synthetic precursors of Solomonamide A, a cyclic …

Epothilones are 16‐membered macrolides that act as microtubule‐targeting agents to tackle
cancer. Many synthetic analogues have been investigated for their activity, yet often based …

This review reports the synthesis of various bioactive macrocycles, involving ring-closing
metathesis as a key step, developed since ca. 2000. These macrocycles exhibited biological …