Mangiferin (mango) attenuates AOM-induced colorectal cancer in rat's colon by augmentation of apoptotic proteins and antioxidant mechanisms

K Abdul-Aziz Ahmed, AAJ Jabbar, MA Abdulla… - Scientific Reports, 2024 - nature.com
Mangiferin (MF) is a natural C-glucosylxantone compound that has many substantial
curative potentials against numerous illnesses including cancers. The present study's goal is …

A triterpenoid (corosolic acid) ameliorated AOM-mediated aberrant crypt foci in rats: modulation of Bax/PCNA, antioxidant and inflammatory mechanisms

MH Al-Medhtiy, MT Mohammed, MMH M. Raouf… - Journal of Molecular …, 2024 - Springer
Corosolic acid (CA) is a well-known natural pentacyclic triterpene found in numerous
therapeutic plants that can exhibit many bioactivities including anti-inflammatory and anti …

Pinostrobin attenuates azoxymethane-induced colorectal cytotoxicity in rats through augmentation of apoptotic Bax/Bcl-2 proteins and antioxidants

B Ali Abed Wahab, N Ain Salehen… - SAGE Open …, 2023 - journals.sagepub.com
Objectives: Pinostrobin (5-hydroxy-7-methoxyflavanone; PN) is a natural active ingredient
with numerous biological activities extensively utilized in tumour chemotherapy. The present …

Sinomenine accelerate wound healing in rats by augmentation of antioxidant, anti-inflammatory, immunuhistochemical pathways

AA Jabbar, KAA Ahmed, MA Abdulla, FO Abdullah… - Heliyon, 2024 - cell.com
Sinomenine (SN) is a well-documented unique plant alkaloid extracted from many herbal
medicines. The present study evaluates the wound healing potentials of SN on dorsal neck …

Apoptosis-driven synergistic anti-cancer efficacy of ethyl acetate extract of Memecylon sisparense Gamble leaves and doxorubicin in in-vitro and in-vivo models of …

JL Uppu, VS Challa, NP Syamprasad… - … -Research and Practice, 2024 - Elsevier
In the spectrum of breast neoplasms, approximately 15 to 20% of all diagnosed cases are
triple-negative breast carcinoma. TNBC grows and spreads faster than other invasive breast …

Bioactive Compounds of Plantago arenaria and Their Effects on SH-SY5Y Cells: Phenolic Content and Docking Analysis

ZB Sarı, ME Sarı, EI Torunoğlu, G Demirel, B Aydın… - Chemistry Africa, 2024 - Springer
This study investigated the antioxidant activity, phenolic content, and cytotoxic effects of
Plantago arenaria extracts, alongside the identification of bioactive compounds and their …

A bitter flavonoid gum from Dorema aucheri accelerate wound healing in rats: Involvement of Bax/HSP 70 and hydroxyprolin mechanisms

KAA Ahmed, AA Jabbar, MMHM Raouf… - Skin Research and …, 2024 - Wiley Online Library
Background Dorema aucheri gum (DAG) is a bitter flavonoid gum widely used for numerous
medicinal purposes including wound recovery. The present work investigates the acute …

[HTML][HTML] Pinostrobin attenuates azoxymethane-induced colorectal cytotoxicity in rats through augmentation of apoptotic Bax/Bcl-2 proteins and antioxidants

BAA Wahab, NA Salehen, MA Abdulla… - SAGE Open …, 2023 - ncbi.nlm.nih.gov
Objectives: Pinostrobin (5-hydroxy-7-methoxyflavanone; PN) is a natural active ingredient
with numerous biological activities extensively utilized in tumour chemotherapy. The present …

Phytochemical Profiling, Acute Toxicity, and Hepatoprotective Effects of Anchusa Limbata in Thioacetamide‐Induced Liver Cirrhosis in Rats

K Abdul‐Aziz Ahmed, AAJ Jabbar… - Food Science & …, 2024 - Wiley Online Library
Evaluation of Anchusa species of the family Boraginaceae during previous investigations
determined numerous therapeutic potentials against inflammatory‐related diseases. The …

Wood calamint ameliorates ethanol-induced stomach injury in rats by augmentation of hsp/bax and inflammatory mechanisms

KAA Ahmed, AAJ Jabbar, MMH M. Raouf… - Journal of Molecular …, 2024 - Springer
Clinopodium menthifolium (wood calamint) is a folkloric medicinal plant ingested as a
treatment for many human disorders including gastric disorders. Our study evaluates the anti …