The endoplasmic reticulum (ER) has a remarkably complex structure, composed of a single
bilayer that forms the nuclear envelope, along with a network of sheets and dynamic tubules …

Membrane-bound organelles are a wonderful evolutionary acquisition of the eukaryotic cell,
allowing the segregation of sometimes incompatible biochemical reactions into specific …

The 28 mammalian members of the super-family of transient receptor potential (TRP)
channels are cation channels, mostly permeable to both monovalent and divalent cations …

Store-operated calcium entry (SOCE) is a ubiquitous Ca 2+ entry pathway that is activated in
response to depletion of ER-Ca 2+ stores and critically controls the regulation of …

Calcium influx through plasma membrane store-operated Ca2+ (SOC) channels is triggered
when the endoplasmic reticulum (ER) Ca2+ store is depleted—a homeostatic Ca2+ …

Introduction• I CRAC• Orais• STIM1• STIM2• STIM1, STIM2 and Ca2+ oscillations• TRPCs
and SOCE• Conclusions The process of store‐operated Ca2+ entry (SOCE), whereby Ca2+ …

Introduction: Although n-3 polyunsaturated fatty acids have been widely described as
antiinflammatory fats, little is known about the role of oleic acid in immune system. Aim: The …

The endoplasmic reticulum (ER) is a morphologically and functionally diverse organelle
capable of integrating multiple extracellular and internal signals and generating adaptive …

Transient receptor potential (TRP) channels of multiple subclasses are expressed in the
heart, although their functions are only now beginning to emerge, especially for the TRPC …

Resveratrol (RSV), a natural polyphenol, has been suggested to induce cell cycle arrest and
activate apoptosis‐mediated cell death in several cancer cells, including prostate cancer …