• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

The microbiology, epidemiology, diagnostics, and treatment of infective endocarditis (IE)
have changed significantly since the Duke Criteria were published in 1994 and modified in …

Importance Infective endocarditis occurs in approximately 15 of 100 000 people in the
United States and has increased in incidence. Clinicians must make treatment decisions …

Infective endocarditis (IE), initially described more than 350 years ago, involves infection of
the endocardial surface of the heart. The clinical manifestations of IE can involve every …

Infective endocarditis is a relatively rare, but deadly cause of sepsis, with an overall mortality
ranging from 20 to 25% in most series. Although the classic clinical classification into …

The coronavirus disease 2019 (COVID-19) pandemic created an unprecedented disruption
to routine patient care (1). Health care professionals scrambled within weeks to attend to the …

Infective endocarditis (IE) is a rare but potentially life-threatening disease, sometimes with
longstanding sequels among surviving patients. The population at high risk of IE is …

Cancer patients and survivors have elevated cardiovascular risk when compared with
noncancer patients. Cardio-oncology has emerged as a new subspecialty to comanage and …

Multimodality imaging plays a pivotal role in the evaluation and management of infective
endocarditis (IE)—a condition with high morbidity and mortality. The diagnosis of IE is …

Non-bacterial thrombotic endocarditis (NBTE), also known as Libman-Sacks, marantic,
thrombotic, or verrucous endocarditis, is a form of non-infective endocarditis that affects …