Gene electrotransfer is a powerful method of DNA delivery offering several medical
applications, among the most promising of which are DNA vaccination and gene therapy for …

Electroporation is being successfully used in biology, medicine, food processing, and
biotechnology, and in some environmental applications. Recent applications also include in …

DNA vaccines are a rapidly deployed next generation vaccination platform for treatment of
human and animal disease. DNA delivery devices, such as electroporation and needle free …

Electrotransfection (ET) is a nonviral method for delivery of various types of molecules into
cells both in vitro and in vivo. Close to 90 clinical trials that involve the use of ET have been …

Electroporation or pulsed electric field (PEF) treatment is a method of treating biological cells
and tissue that, due to its nonthermal nature, facilitates preservation of natural qualities such …

The exact mechanisms of nucleic acid (NA) delivery with gene electrotransfer (GET) are still
unknown, which represents a limitation for its broader use. Further, not knowing the effects …

In many electroporation applications mass transport in biological tissue is of primary
concern. This paper presents a theoretical advancement in the field and gives some …

The majority of studies on lethal radiobiological damage have focused on double-strand
breaks (DSBs), a type of clustered DNA damage and the evaluation of their toxicity, while …

Application of electric pulses (electroporation/electropermeabilization) is an effective method
for gene transfer (ie gene electrotransfer (GET)) in vitro and in vivo. Currently, the …

The great interest for naked plasmid DNA in gene therapy studies is reflected by the fact that
it is currently used in 18% of all gene therapy trials. Therefore, validation of topology and …