Target based chemotherapeutic advancement of ruthenium complexes

BK Kundu, S Mukhopadhyay - Coordination Chemistry Reviews, 2021 - Elsevier
Over the last few years, great emphasis has been given to develop ruthenium complexes to
act as target specified chemotherapeutic agents. Indeed, there are few reviews available …

Second and third-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumour activity

GV Suárez-Moreno, D Hernández-Romero… - Coordination Chemistry …, 2022 - Elsevier
The application of metal compounds in the medical field dates back to the XVI century with
some isolated reports about the therapeutic importance of metals and their compounds in …

Synthesis, crystallographic structure, theoretical analysis, molecular docking studies, and biological activity evaluation of binuclear Ru (II)-1-naphthylhydrazine …

T Eichhorn, F Kolbe, S Mišić, D Dimić, I Morgan… - International journal of …, 2022 - mdpi.com
Ruthenium (II)–arene complexes have gained significant research interest due to their
possible application in cancer therapy. In this contribution two new complexes are …

Recent Trends in the development of novel metal-based antineoplastic drugs

L Todorov, I Kostova - Molecules, 2023 - mdpi.com
Since the accidental discovery of the anticancer properties of cisplatin more than half a
century ago, significant efforts by the broad scientific community have been and are currently …

Influence of Indole-N Substitution of Thiosemicarbazones in Cationic Ru(II)(η6-Benzene) Complexes on Their Anticancer Activity

N Balakrishnan, J Haribabu, M Dharmasivam… - …, 2023 - ACS Publications
Indole thiosemicarbazones (TSCs) and their complexes are known to possess various
biological activities. The variation in anticancer activity with different indole-N substituents of …

Mitochondria-targeting click-derived pyridinyltriazolylmethylquinoxaline-based Y-shaped binuclear luminescent ruthenium (II) and iridium (III) complexes as cancer …

N Roy, U Sen, Y Madaan, V Muthukumar… - Inorganic …, 2020 - ACS Publications
Due to several negative issues, market available drugs have been gradually losing their
importance in the treatment of cancer. With a view to discover suitable drugs capable of …

Ethanol as hydrogen donor: An efficient transfer hydrogenation of aldehydes, ketones, and nitroarenes with H-bonded Ru (II)-N-heterocyclic iminium complex

S Revathi, T Ghatak - Journal of Catalysis, 2024 - Elsevier
Isopropanol and formic acid are predominantly utilized as hydrogen sources in catalytic
transfer hydrogenation reactions. However, the utilization of primary alcohols in such …

Luminescent 11-{Naphthalen-1-yl} dipyrido [3, 2-a: 2′, 3′-c] phenazine-Based Ru (II)/Ir (III)/Re (I) Complexes for HCT-116 Colorectal Cancer Stem Cell Therapy

U Das, S Shanavas, AH Nagendra, B Kar… - ACS Applied Bio …, 2023 - ACS Publications
Due to a number of unpleasant considerations, marketed drugs have steadily lost their
importance in the treatment of cancer. In order to find a viable cancer cell diagnostic agent …

Current scenario of 1, 3-oxazole derivatives for anticancer activity

X Yan, J Wen, L Zhou, L Fan… - Current Topics in …, 2020 - ingentaconnect.com
Cancer, which has been cursed for human beings for long time is considered as one of the
leading causes of morbidity and mortality across the world. In spite of different types of …

Nanoencapsulation of Ru(p-cymene) Complex Bearing Ginger-based Natural Product into Liposomal Nanoformulation to Improve Its Cellular Uptake and …

C Sumithaa, T Manjunathan, O Mazuryk… - ACS Applied Bio …, 2022 - ACS Publications
The organometallic compounds are prospective candidates in the row of developing
metallochemotherapeutics with the aim of overcoming the limitations of platinum drugs. In …