Ang-1 and VEGF: central regulators of angiogenesis

Y Zhao, B Yu, Y Wang, S Tan, Q Xu, Z Wang… - Molecular and Cellular …, 2024 - Springer
Abstract Angiopoietin-1 (Ang-1) and Vascular Endothelial Growth Factor (VEGF) are central
regulators of angiogenesis and are often inactivated in various cardiovascular diseases …

Angiogenic activity of mitochondria; beyond the sole bioenergetic organelle

F Sadeghsoltani, P Hassanpour… - Journal of Cellular …, 2024 - Wiley Online Library
Angiogenesis is a complex process that involves the expansion of the pre‐existing vascular
plexus to enhance oxygen and nutrient delivery and is stimulated by various factors …

[HTML][HTML] VEGF, but Not BDNF, Prevents the Downregulation of KCC2 Induced by Axotomy in Extraocular Motoneurons

J Capilla-López, RG Hernández… - International …, 2024 - pmc.ncbi.nlm.nih.gov
The potassium–chloride cotransporter KCC2 is the main extruder of Cl-in neurons. It plays a
fundamental role in the activity of the inhibitory neurotransmitters (GABA and glycine) since …

[HTML][HTML] Gene Therapy for Parkinson's Disease Using Midbrain Developmental Genes to Regulate Dopaminergic Neuronal Maintenance

J Kim, MY Chang - International Journal of Molecular Sciences, 2024 - mdpi.com
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder. It is
characterized by the progressive loss of dopaminergic (DAnergic) neurons in the substantia …

New evidence of vascular defects in neurodegenerative diseases revealed by single cell RNA sequencing

J Qiu, S Peng, R Qu, L Wu, L Xing, L Zhang… - Clinical …, 2024 - portlandpress.com
Neurodegenerative diseases (NDs) involve the progressive loss of neuronal structure or
function in the brain and spinal cord. Despite their diverse etiologies, NDs manifest similar …

In vivo evidence of increased vascular endothelial growth factor in patients with major depressive disorder

K Li, K Wang, S Xu, X Xie, Y Tang, L Zhang… - Journal of Affective …, 2025 - Elsevier
Background Vascular endothelial growth factor (VEGF) is a candidate mediator of blood-
brain barrier (BBB) disruption in depression. However, previous studies have mainly …

Inhibition of Vascular Endothelial Growth Factor Reduces Photoreceptor Death in Retinal Neovascular Disease via Neurotrophic Modulation in Müller Glia

S Gao, S Gao, Y Wang, L Xiang, H Peng, G Chen… - Molecular …, 2025 - Springer
VEGF is not only the most potent angiogenic factor, but also an important neurotrophic
factor. In this study, vitreous expression of six neurotrophic factors were examined in …

[HTML][HTML] Growth Factors and Their Application in the Therapy of Hereditary Neurodegenerative Diseases

S Issa, H Fayoud, A Shaimardanova, A Sufianov… - Biomedicines, 2024 - mdpi.com
Hereditary neurodegenerative diseases (hNDDs) such as Alzheimer's, Parkinson's,
Huntington's disease, and others are primarily characterized by their progressive nature …

Cerebrovascular Remodeling and the Role of Vascular Endothelial Growth Factor in the Epileptic Brain and Pharmacoresistance

JL Castañeda-Cabral, ME Ureña-Guerrero… - … in Epilepsy: From …, 2023 - Springer
The neurovascular unit plays a relevant role in normal situations and pathological conditions
involving the nervous system. In epileptic conditions, cerebrovascular remodeling is a …

Platelet-rich fibrin in dentistry

P Song, D He, S Ren, L Fan… - Journal of Applied …, 2024 - journals.sagepub.com
Objectives: To review the progress of Platelet Rich Fibrin (PRF) as a biomaterial in dentistry
and to highlight its promising application as a safe and biocompatible autologous platelet …