Oxidation-reduction mechanisms in psychiatric disorders: A novel target for pharmacological intervention

AC Rossetti, MS Paladini, MA Riva, R Molteni - Pharmacology & …, 2020 - Elsevier
While neurotransmitter dysfunction represents a key component in mental illnesses, there is
now a wide agreement for a central pathophysiological hub that includes hormones …

[HTML][HTML] Glucocorticoid programming of neuroimmune function

DJ Walker, KA Spencer - General and comparative endocrinology, 2018 - Elsevier
Throughout life physiological systems strive to maintain homeostasis and these systems are
susceptible to exposure to maternal or environmental perturbations, particularly during …

[PDF][PDF] Age and sex-specific effects of maternal deprivation on memory and oxidative stress in the hippocampus of rats

A Nassiri, M Lamtai, I Berkiks… - International Journal of …, 2023 - iscientific.org
Early-life stress (ELS) is a risk factor for a variety of neuropsychiatric disturbances, including
anxiety and depression. ELS in the form of maternal deprivation (MD) can be linked also to …

[PDF][PDF] Age and sex dependent effects of maternal deprivation on anxiety-like and depressive-like behaviors and oxidative stress in the prefrontal cortex of rats

A Nassiri, M Lamtai, I Berkiks, H Benmhammed… - Adv. Anim. Vet …, 2024 - researchgate.net
Early life stress, represented by maternal deprivation (MD), is associated with numerous
behavioral disorders in later life. In young adulthood, a single 24-hour period of MD has …

Maternal separation induces long-term oxidative stress alterations and increases anxiety-like behavior of male Balb/cJ mice

LMC Malcon, LE Wearick-Silva, A Zaparte… - Experimental Brain …, 2020 - Springer
Early life stress (ELS) exposure is a well-known risk factor for the development of psychiatric
conditions, including anxiety disorder. Preclinical studies show that maternal separation …

Proteome profiling of different rat brain regions reveals the modulatory effect of prolonged maternal separation on proteins involved in cell death-related processes

Z Drastichova, V Rudajev, G Pallag, J Novotny - Biological research, 2021 - SciELO Chile
Resumen DRASTICHOVA, Zdenka; RUDAJEV, Vladimir; PALLAG, Gergely y NOVOTNY,
Jiri. Proteome profiling of different rat brain regions reveals the modulatory effect of …

Maternal deprivation in rats decreases the expression of interneuron markers in the neocortex and hippocampus

M Aksic, J Poleksic, D Aleksic, N Petronijevic… - Frontiers in …, 2021 - frontiersin.org
Early life stress has profound effects on the development of the central nervous system. We
exposed 9-day-old rat pups to a 24 h maternal deprivation (MD) and sacrificed them as …

Animal Model of Autism Induced by Valproic Acid Combined with Maternal Deprivation: Sex-Specific Effects on Inflammation and Oxidative Stress

JMB Campos, M de Aguiar da Costa… - Molecular …, 2024 - Springer
Autism spectrum disorder (ASD) etiology probably involves a complex interplay of both
genetic and environmental risk factors, which includes pre-and perinatal exposure to …

Environmental enrichment rescues oxidative stress and behavioral impairments induced by maternal care deprivation: Sex-and developmental-dependent differences

GZ Réus, MS Abitante, LM Manosso… - Molecular …, 2021 - Springer
Stress is related to major depressive disorder (MDD). This study investigated the action that
early stress, represented by maternal deprivation (MD), has on the behavior and oxidative …

The long-term effects of maternal deprivation on the number and size of inhibitory interneurons in the rat amygdala and nucleus accumbens

D Aleksic, J Poleksic, G Agatonovic, V Djulejic… - Frontiers in …, 2023 - frontiersin.org
Introduction There is an increasing evidence supporting the hypothesis that traumatic
experiences during early developmental periods might be associated with psychopathology …