The global production of plastics has continuously been soaring over the last decades due
to their extensive use in our daily life and in industries. Although synthetic plastics offer great …

The rise of the “Top Down” method in the field of mass spectrometry-based proteomics has
ushered in a new age of promise and challenge for the characterization and identification of …

Mass spectrometry (MS)–based high-throughput proteomics is the core technique for large-
scale protein characterization. Due to the extreme complexity of proteomes, sophisticated …

In this review, we present recent advancements and novel developments in fluidic systems
for applied analytical purposes in chemistry, biochemistry, and life science in general that …

The analysis of proteins in biological samples is highly desirable, given their connection to
myriad biological functions and disease states, as well as the growing interest in the …

The study of proteins is one of the most challenging tasks in analytical chemistry. The initial
protein research focused on developing techniques that could separate and identify the …

Top Down mass spectrometry (MS) has emerged as an alternative to common Bottom Up
strategies for protein analysis. In the Top Down approach, intact proteins are fragmented …

The identification, quantitation and global characterisation of all proteins within a given
proteome are extremely challenging. This is due to the absolute detection limits of …

CE coupled to MS has proven to be a powerful analytical tool for the characterization of
intact proteins, as it combines the high separation efficiency of CE with the selectivity of MS …

With the acceleration of proteome research, increasing attention has been paid to
multidimensional liquid chromatography–mass spectrometry (MDLC–MS) due to its high …