The number of mesenchymal stromal/stem cell (MSC) therapeutics and types of clinical
applications have greatly diversified during the past decade, including rapid growth of poorly …

Mesenchymal stromal cells (MSCs) have gained immense attention over the past two
decades due to their multipotent differentiation potential and pro-regenerative and …

Oncogenes destabilize STING in epithelial cell-derived cancer cells, such as head and neck
squamous cell carcinomas (HNSCCs), to promote immune escape. Despite the abundance …

Mesenchymal stromal cells (MSCs) possess several fairly unique properties that, when
combined, make them ideally suited for cellular-based immunotherapy and as vehicles for …

Background Immunomodulation by mesenchymal stromal cells (MSCs) can occur through
trophic factor mechanisms, however, intravenously infused MSCs are rapidly cleared from …

Polychlorinated biphenyl (PCB) accumulates in adipose where it may impact the growth and
function of cells within the tissue. This is particularly concerning during adolescence when …

Mesenchymal stromal cells (MSCs) are administered locally to treat sites of inflammation.
Local delivery is known to cause MSCs to aggregate into “spheroids,” which alters gene …

Diabetes mellitus and its complications pose a major threat to global health and affect the
quality of life and life expectancy of patients. Currently, the application of traditional …

Mesenchymal stromal cells (MSCs) showcase remarkable immunoregulatory capabilities in
vitro, positioning them as promising candidates for cellular therapeutics. However, the …

Human mesenchymal stromal cells (MSCs) are a leading cell therapy candidate for the
treatment of immune and inflammatory diseases due to their potent regulation of immune …