Deep neural networks represent, nowadays, the most effective machine learning technology in biomedical domain. In this domain, the different areas of interest concern the Omics (study …
Drug-target interaction (DTI) prediction plays a crucial role in drug repositioning and virtual drug screening. Most DTI prediction methods cast the problem as a binary classification task …
A Saxena - Journal of biosciences, 2020 - Springer
The current global pandemic COVID-19 caused by the SARS-CoV-2 virus has already inflicted insurmountable damage both to the human lives and global economy. There is an …
Drug–target interaction (DTI) prediction is a crucial step in drug discovery and repositioning as it reduces experimental validation costs if done right. Thus, developing in-silico methods …
In silico prediction of drug–target interactions is a critical phase in the sustainable drug development process, especially when the research focus is to capitalize on the …
H Abbasi Mesrabadi, K Faez, J Pirgazi - Scientific Reports, 2023 - nature.com
Drug–target interaction prediction is a vital stage in drug development, involving lots of methods. Experimental methods that identify these relationships on the basis of clinical …
Y Qian, X Li, J Wu, Q Zhang - BMC bioinformatics, 2023 - Springer
Background Prediction of drug–target interaction (DTI) is an essential step for drug discovery and drug reposition. Traditional methods are mostly time-consuming and labor-intensive …
A Sharma, R Rani - Computer methods and programs in biomedicine, 2018 - Elsevier
Background and objective Drug-target interaction prediction plays an intrinsic role in the drug discovery process. Prediction of novel drugs and targets helps in identifying optimal …
Hoy en día, las redes neuronales artificiales y el deep learning, son dos de las herramientas más poderosas del aprendizaje de máquina, que tienen por objetivo desarrollar sistemas …