Machine learning approaches and databases for prediction of drug–target interaction: a survey paper

M Bagherian, E Sabeti, K Wang… - Briefings in …, 2021 - academic.oup.com
The task of predicting the interactions between drugs and targets plays a key role in the
process of drug discovery. There is a need to develop novel and efficient prediction …

Deep learning in the biomedical applications: Recent and future status

R Zemouri, N Zerhouni, D Racoceanu - Applied Sciences, 2019 - mdpi.com
Deep neural networks represent, nowadays, the most effective machine learning technology
in biomedical domain. In this domain, the different areas of interest concern the Omics (study …

Affinity2Vec: drug-target binding affinity prediction through representation learning, graph mining, and machine learning

MA Thafar, M Alshahrani, S Albaradei, T Gojobori… - Scientific reports, 2022 - nature.com
Drug-target interaction (DTI) prediction plays a crucial role in drug repositioning and virtual
drug screening. Most DTI prediction methods cast the problem as a binary classification task …

Drug targets for COVID-19 therapeutics: Ongoing global efforts

A Saxena - Journal of biosciences, 2020 - Springer
The current global pandemic COVID-19 caused by the SARS-CoV-2 virus has already
inflicted insurmountable damage both to the human lives and global economy. There is an …

DTi2Vec: Drug–target interaction prediction using network embedding and ensemble learning

MA Thafar, RS Olayan, S Albaradei, VB Bajic… - Journal of …, 2021 - Springer
Drug–target interaction (DTI) prediction is a crucial step in drug discovery and repositioning
as it reduces experimental validation costs if done right. Thus, developing in-silico methods …

DTiGEMS+: drug–target interaction prediction using graph embedding, graph mining, and similarity-based techniques

MA Thafar, RS Olayan, H Ashoor, S Albaradei… - Journal of …, 2020 - Springer
In silico prediction of drug–target interactions is a critical phase in the sustainable drug
development process, especially when the research focus is to capitalize on the …

Drug–target interaction prediction based on protein features, using wrapper feature selection

H Abbasi Mesrabadi, K Faez, J Pirgazi - Scientific Reports, 2023 - nature.com
Drug–target interaction prediction is a vital stage in drug development, involving lots of
methods. Experimental methods that identify these relationships on the basis of clinical …

MCL-DTI: using drug multimodal information and bi-directional cross-attention learning method for predicting drug–target interaction

Y Qian, X Li, J Wu, Q Zhang - BMC bioinformatics, 2023 - Springer
Background Prediction of drug–target interaction (DTI) is an essential step for drug discovery
and drug reposition. Traditional methods are mostly time-consuming and labor-intensive …

BE-DTI': Ensemble framework for drug target interaction prediction using dimensionality reduction and active learning

A Sharma, R Rani - Computer methods and programs in biomedicine, 2018 - Elsevier
Background and objective Drug-target interaction prediction plays an intrinsic role in the
drug discovery process. Prediction of novel drugs and targets helps in identifying optimal …

[PDF][PDF] Aplicaciones de las redes neuronales y el deep learning a la ingeniería biomédica

JL Sarmiento-Ramos - Revista UIS Ingenierías, 2020 - redalyc.org
Hoy en día, las redes neuronales artificiales y el deep learning, son dos de las herramientas
más poderosas del aprendizaje de máquina, que tienen por objetivo desarrollar sistemas …