Industrial potential of the enzymatic synthesis of nucleoside analogs: Existing challenges and perspectives
Nucleoside phosphorylases have progressed from an enzymatic curiosity to a viable
synthetic tool. However, despite the recent advances in nucleoside phosphorylase …
synthetic tool. However, despite the recent advances in nucleoside phosphorylase …
Detection of microbial contamination based on uracil-selective synthetic receptors
J Bezdekova, M Vodova, K Dolezelikova, J Zitka… - Talanta, 2021 - Elsevier
The here presented work is focused on the development of a method for detection of
microbial contamination of food based on uracil-selective synthetic receptors. Because …
microbial contamination of food based on uracil-selective synthetic receptors. Because …
Biosynthesis of nucleoside analogues via thermostable nucleoside phosphorylase
S Zhu, D Song, C Gong, P Tang, X Li, J Wang… - Applied microbiology …, 2013 - Springer
Biocatalyzed synthesis of nucleoside analogues was carried out using two thermostable
nucleoside phosphorylases from the hyperthermophilic aerobic crenarchaeon Aeropyrum …
nucleoside phosphorylases from the hyperthermophilic aerobic crenarchaeon Aeropyrum …
High-syn conformation of uridine and asymmetry of the hexameric molecule revealed in the high-resolution structures of Shewanella oneidensis MR-1 uridine …
TN Safonova, SN Mikhailov, VP Veiko… - … Section D: Biological …, 2014 - journals.iucr.org
Uridine phosphorylase (UP; EC 2.4. 2.3), a key enzyme in the pyrimidine-salvage pathway,
catalyzes the reversible phosphorolysis of uridine to uracil and ribose 1-phosphate …
catalyzes the reversible phosphorolysis of uridine to uracil and ribose 1-phosphate …
Crystallization of uridine phosphorylase from Shewanella oneidensis MR-1 in the laboratory and under microgravity and preliminary X-ray diffraction analysis
TN Safonova, NN Mordkovich… - … Section F: Structural …, 2012 - journals.iucr.org
Uridine phosphorylase (UDP, EC 2.4. 2.3), a key enzyme in the pyrimidine salvage pathway,
catalyses the reversible phosphorolysis of uridine to uracil and ribose 1-phosphate. The …
catalyses the reversible phosphorolysis of uridine to uracil and ribose 1-phosphate. The …
Uridine Phosphorylase from Trypanosoma cruzi: Kinetic and Chemical Mechanisms
RG Silva, VL Schramm - Biochemistry, 2011 - ACS Publications
The reversible phosphorolysis of uridine to generate uracil and ribose 1-phosphate is
catalyzed by uridine phosphorylase and is involved in the pyrimidine salvage pathway. We …
catalyzed by uridine phosphorylase and is involved in the pyrimidine salvage pathway. We …
Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici
C Yang, J Li, Z Huang, X Zhang, X Gao, C Zhu… - Scientific Reports, 2020 - nature.com
Uridine phosphorylase (UP) is a key enzyme of pyrimidine salvage pathways that enables
the recycling of endogenous or exogenous-supplied pyrimidines and plays an important …
the recycling of endogenous or exogenous-supplied pyrimidines and plays an important …
Concerted action of two subunits of the functional dimer of Shewanella oneidensis MR-1 uridine phosphorylase derived from a comparison of the C212S mutant and …
TN Safonova, NN Mordkovich, VP Veiko… - … Section D: Structural …, 2016 - journals.iucr.org
Uridine phosphorylase (UP; EC 2.4. 2.3), a key enzyme in the pyrimidine-salvage pathway,
catalyzes the reversible phosphorolysis of uridine to uracil and ribose 1-phosphate. The …
catalyzes the reversible phosphorolysis of uridine to uracil and ribose 1-phosphate. The …
The evolution of catalytic residues and enzyme mechanism within the bacterial nucleoside phosphorylase superfamily 1
A Konrad, J Piškur, DA Liberles - Gene, 2012 - Elsevier
Nucleoside phosphorylases are essential for the salvage and catabolism of nucleotides in
bacteria and other organisms, and members of this enzyme superfamily have been of …
bacteria and other organisms, and members of this enzyme superfamily have been of …
[HTML][HTML] Enzymatic synthesis and phosphorolysis of 4 (2)-thioxo-and 6 (5)-azapyrimidine nucleosides by E. coli nucleoside phosphorylases
VA Stepchenko, AI Miroshnikov, F Seela… - Beilstein Journal of …, 2016 - beilstein-journals.org
Abstract The trans-2-deoxyribosylation of 4-thiouracil (4S Ura) and 2-thiouracil (2S Ura), as
well as 6-azauracil, 6-azathymine and 6-aza-2-thiothymine was studied using dG and E. coli …
well as 6-azauracil, 6-azathymine and 6-aza-2-thiothymine was studied using dG and E. coli …