[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach… - Redox biology, 2017 - Elsevier
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Is nitric oxide overproduction the target of choice for the management of septic shock?

F Feihl, B Waeber, L Liaudet - Pharmacology & therapeutics, 2001 - Elsevier
Sepsis is a heterogeneous class of syndromes caused by a systemic inflammatory response
to infection. Septic shock, a severe form of sepsis, is associated with the development of …

Angiotensin II hypertension is attenuated in interleukin-6 knockout mice

DL Lee, LC Sturgis, H Labazi… - American Journal …, 2006 - journals.physiology.org
Plasma levels of IL-6 correlate with high blood pressure under many circumstances, and
ANG II has been shown to stimulate IL-6 production from various cell types. This study tested …

Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog

FA Recchia, PI McConnell, RD Bernstein… - Circulation …, 1998 - Am Heart Assoc
The aim of the present study was to determine whether cardiac nitric oxide (NO) production
changes during the progression of pacing-induced heart failure and whether this occurs in …

Effects of propofol on hemodynamic and inflammatory responses to endotoxemia in rats

T Taniguchi, K Yamamoto, N Ohmoto, K Ohta… - Critical care …, 2000 - journals.lww.com
Objective: To document the effects of propofol on the hemodynamic and inflammatory
responses to endotoxemia in an animal model. Design: Randomized, prospective laboratory …

Reduced endothelial NO-cGMP–mediated vascular relaxation and hypertension in IL-6–infused pregnant rats

JM Orshal, RA Khalil - Hypertension, 2004 - Am Heart Assoc
Placental ischemia during pregnancy is associated with increased plasma cytokines such as
interleukin-6 (IL-6), which may contribute to increased vascular resistance and hypertension …

Ketamine inhibits endotoxin-induced shock in rats.

T Taniguchi, K Shibata, K Yamamoto - Anesthesiology, 2001 - europepmc.org
Background Cytokines and nitric oxide are believed to participate importantly in the
pathogenesis of endotoxin-induced shock. Several investigators have documented that …

Myocardial dysfunction in septic shock: Part II. Role of cytokines and nitric oxide

A Kumar, A Krieger, S Symeoneides… - … of cardiothoracic and …, 2001 - jcvaonline.com
From the Division of Cardiovascular Diseases and Critical Care Medicine, Department of
Medicine, Rush–Presbyterian–St. Luke's Medical Center, Chicago; and Finch University of …

Interleukin-6 impairs endothelium-dependent NO-cGMP-mediated relaxation and enhances contraction in systemic vessels of pregnant rats

JM Orshal, RA Khalil - American Journal of Physiology …, 2004 - journals.physiology.org
IL-6 is elevated in plasma of preeclamptic women, and twofold elevation of plasma IL-6
increases vascular resistance and arterial pressure in pregnant rats, suggesting a role of the …

Neuroinflammation in the NTS is associated with changes in cardiovascular reflexes during systemic inflammation

MR Amorim, JL de Deus, RA Cazuza… - Journal of …, 2019 - Springer
Background Lipopolysaccharide (LPS)-induced systemic inflammation (SI) is associated
with neuroinflammation in the brain, hypotension, tachycardia, and multiple organs …