MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

Acute myeloid leukemia (AML) is a deadly hematologic malignancy characterized by the
uncontrolled growth of immature myeloid cells. Over the past several decades, we have …

Hematologic malignancies are one of the most common cancers, and the incidence has
been rising in recent decades. The clinical and molecular features of hematologic …

Acute leukaemias are characterized by recurring chromosomal aberrations and gene
mutations that are crucial to disease pathogenesis. It is now evident that epigenetic …

Expression of microRNAs, a new class of noncoding RNAs that hybridize to target
messenger RNA and regulate their translation into proteins, has been recently demonstrated …

The purpose of this book is to present a new mechanistic theory of mutation-driven evolution
based on recent advances in genomics and evolutionary developmental biology. The theory …

Expression of microRNAs (miRNAs) is under stringent regulation at both transcriptional and
posttranscriptional levels. Disturbance at either level could cause dysregulation of miRNAs …

MicroRNAs (miRNAs) regulate dendritogenesis and plasticity. However, the biological
function of miRNAs in axons has not been extensively investigated. Here, using rat primary …

Increased expression levels of miR-181 family members have been shown to be associated
with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here …

Embryos of the echinoderms, especially those of sea urchins and sea stars, have been
studied as model organisms for over 100 years. The simplicity of their early development …