Global epidemiology of cirrhosis—aetiology, trends and predictions

DQ Huang, NA Terrault, F Tacke, LL Gluud… - Nature reviews …, 2023 - nature.com
Cirrhosis is an important cause of morbidity and mortality in people with chronic liver
disease worldwide. In 2019, cirrhosis was associated with 2.4% of global deaths. Owing to …

Worldwide prevalence of hepatitis B virus and hepatitis C virus among patients with cirrhosis at country, region, and global levels: a systematic review

CJ Alberts, GM Clifford, D Georges, F Negro… - The Lancet …, 2022 - thelancet.com
Background Empirical, updated country-level estimates on the proportion of cirrhosis
attributable to viral hepatitis are required. We estimated the prevalence of hepatitis B virus …

[HTML][HTML] Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma

YH Yeo, JS Samaan, WH Ng, PS Ting… - Clinical and …, 2023 - ncbi.nlm.nih.gov
Methods ChatGPT's responses to 164 questions were independently graded by two
transplant hepatologists and resolved by a third reviewer. The performance of ChatGPT was …

[HTML][HTML] Epidemiology of liver cirrhosis and associated complications: Current knowledge and future directions

YB Liu, MK Chen - World journal of gastroenterology, 2022 - ncbi.nlm.nih.gov
Cirrhosis causes a heavy global burden. In this review, we summarized up-to-date
epidemiological features of cirrhosis and its complications. Recent epidemiological studies …

Cope with copper: From copper linked mechanisms to copper-based clinical cancer therapies

X Wang, M Zhou, Y Liu, Z Si - Cancer Letters, 2023 - Elsevier
Recent studies have established a strong link between copper and cancer biology, as
copper is necessary for cancer growth and metastasis. Beyond the conventional concept of …

Macrophage autophagy in macrophage polarization, chronic inflammation and organ fibrosis

JH Wen, DY Li, S Liang, C Yang, JX Tang… - Frontiers in …, 2022 - frontiersin.org
As the essential regulators of organ fibrosis, macrophages undergo marked phenotypic and
functional changes after organ injury. These changes in macrophage phenotype and …

The NLRP3 inflammasome: contributions to inflammation-related diseases

Y Chen, X Ye, G Escames, W Lei, X Zhang, M Li… - Cellular & molecular …, 2023 - Springer
The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that regulates
innate immune responses by activating caspase-1 and the inflammatory cytokines …

Oxidative stress in liver pathophysiology and disease

A Allameh, R Niayesh-Mehr, A Aliarab, G Sebastiani… - Antioxidants, 2023 - mdpi.com
The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Association between SII and hepatic steatosis and liver fibrosis: a population-based study

R Xie, M Xiao, L Li, N Ma, M Liu, X Huang… - Frontiers in …, 2022 - frontiersin.org
Background The systemic immune-inflammation index (SII) is a novel marker of
inflammation, and hepatic steatosis and fibrosis are associated with inflammation. This study …

Development, validation, and prognostic evaluation of a risk score for long-term liver-related outcomes in the general population: a multicohort study

M Serra-Burriel, A Juanola, F Serra-Burriel, M Thiele… - The Lancet, 2023 - thelancet.com
Background Liver cirrhosis is a major cause of death worldwide. Cirrhosis develops after a
long asymptomatic period of fibrosis progression, with the diagnosis frequently occurring …