Q Nevers, AA Albertini, C Lagaudrière-Gesbert… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Viruses reshape the organization of the cell interior to achieve different steps of their cellular cycle. Particularly, viral replication and assembly often take place in viral factories where …
S Jain, E Martynova, A Rizvanov, S Khaiboullina… - Pathogens, 2021 - mdpi.com
Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented, single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …
O Dolnik, GK Gerresheim, N Biedenkopf - Cells, 2021 - mdpi.com
Infections by negative strand RNA viruses (NSVs) induce the formation of viral inclusion bodies (IBs) in the host cell that segregate viral as well as cellular proteins to enable efficient …
F Almeida-Pinto, R Pinto, J Rocha - Infectious Diseases and Therapy, 2024 - Springer
In 1976 Ebola revealed itself to the world, marking the beginning of a series of localized outbreaks. However, it was the Ebola outbreak that began in 2013 that incited fear and …
D Loh, RJ Reiter - International journal of molecular sciences, 2022 - mdpi.com
The relentless, protracted evolution of the SARS-CoV-2 virus imposes tremendous pressure on herd immunity and demands versatile adaptations by the human host genome to counter …
L Wendt, J Brandt, DS Ushakov, BS Bodmer… - Journal of …, 2022 - Am Soc Microbiol
Many negative-sense RNA viruses, including the highly pathogenic Ebola virus (EBOV), use cytoplasmic inclusion bodies (IBs) for viral RNA synthesis. However, it remains unclear how …
With the gradual increase in the COVID-19 mortality rate, there is an urgent need for an effective drug/vaccine. Several drugs like Remdesivir, Azithromycin, Favirapir, Ritonavir …
T Miyake, CM Farley, BE Neubauer… - Journal of …, 2020 - Am Soc Microbiol
Ebola virus (EBOV) inclusion bodies (IBs) are cytoplasmic sites of nucleocapsid formation and RNA replication, housing key steps in the virus life cycle that warrant further …
BS Bodmer, M Vallbracht, DS Ushakov… - Emerging Microbes & …, 2023 - Taylor & Francis
Viral RNA synthesis of several non-segmented, negative-sense RNA viruses (NNSVs) takes place in inclusion bodies (IBs) that show properties of liquid organelles, which are formed by …