Anti-angiogenic therapy: current challenges and future perspectives

F Lopes-Coelho, F Martins, SA Pereira… - International journal of …, 2021 - mdpi.com
Anti-angiogenic therapy is an old method to fight cancer that aims to abolish the nutrient and
oxygen supply to the tumor cells through the decrease of the vascular network and the …

Cancer-associated neurogenesis and nerve-cancer cross-talk

DA Silverman, VK Martinez, PM Dougherty, JN Myers… - Cancer research, 2021 - AACR
In this review, we highlight recent discoveries regarding mechanisms contributing to nerve-
cancer cross-talk and the effects of nerve-cancer cross-talk on tumor progression and …

The current knowledge concerning solid cancer and therapy

M Najafi, J Majidpoor, H Toolee… - Journal of biochemical …, 2021 - Wiley Online Library
Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …

Tumor-induced neurogenesis and immune evasion as targets of innovative anti-cancer therapies

RD Cervantes-Villagrana, D Albores-García… - Signal transduction and …, 2020 - nature.com
Normal cells are hijacked by cancer cells forming together heterogeneous tumor masses
immersed in aberrant communication circuits that facilitate tumor growth and dissemination …

Effects of β-Blockers on the Sympathetic and Cytokines Storms in Covid-19

HM Al-Kuraishy, AI Al-Gareeb… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a causative virus in the
development of coronavirus disease 2019 (Covid-19) pandemic. Respiratory manifestations …

Functional two-way crosstalk between brain and lung: the brain–lung axis

C Li, W Chen, F Lin, W Li, P Wang, G Liao… - Cellular and Molecular …, 2023 - Springer
The brain has many connections with various organs. Recent advances have demonstrated
the existence of a bidirectional central nervous system (CNS) and intestinal tract, that is, the …

Drug repurposing for cancer therapy

Y Xia, M Sun, H Huang, WL Jin - Signal Transduction and Targeted …, 2024 - nature.com
Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …

Neurobiology of cancer: the role of β-adrenergic receptor signaling in various tumor environments

B Mravec, L Horvathova, L Hunakova - International journal of molecular …, 2020 - mdpi.com
The development and progression of cancer depends on both tumor micro-and
macroenvironments. In addition, psychosocial and spiritual “environments” might also affect …

Chronic stress in solid tumor development: from mechanisms to interventions

J Yan, Y Chen, M Luo, X Hu, H Li, Q Liu… - Journal of Biomedical …, 2023 - Springer
Chronic stress results in disturbances of body hormones through the neuroendocrine
system. Cancer patients often experience recurrent anxiety and restlessness during disease …

[HTML][HTML] Tumor-associated macrophages: role in tumorigenesis and immunotherapy implications

S Zhu, Z Luo, X Li, X Han, S Shi, T Zhang - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Tumor-associated macrophages (TAMs) occupy an important position in the tumor
microenvironment (TME), they are a highly plastic heterogeneous population with complex …