The microbial decomposition and utilization of lignocellulosic biomass present in the plant
tissues are driven by a series of carbohydrate active enzymes (CAZymes) acting in concert …

Motivation: Protein structure similarity is often measured by root mean squared deviation,
global distance test score and template modeling score (TM-score). However, the scores …

Current societies undergo a transformation into information societies.“Digitialization” is
progressing in every aspect of life, including health care. Handling the increasing flow of …

Proteins are usually described and classified according to amino acid sequence, structure or
function. Here, we develop a minimally biased scheme to compare and classify proteins …

Background Fungal mating types in self-incompatible Pezizomycotina are specified by one
of two alternate sequences occupying the same locus on corresponding chromosomes. One …

Motivation Evolutionary inference depends crucially on the quality of multiple sequence
alignments (MSA), which is problematic for distantly related proteins. Since protein structure …

The ecological role of microorganisms is of utmost importance due to their multiple
interactions with the environment. However, assessing the contribution of individual …

The computational reconstruction of ancestral proteins provides information on past
biological events and has practical implications for biomedicine and biotechnology …

The ancestral sequence reconstruction (ASR) is a molecular evolution technique that
provides applications to a variety of fields such as biotechnology and biomedicine. To infer …

Probabilistic phylogenetic tree reconstruction is traditionally performed under a best-fitting
substitution model of molecular evolution previously selected according to diverse statistical …