The neural stem cell niche defines a zone in which stem cells are retained after embryonic
development for the production of new cells of the nervous system. This continual supply of …

Glioblastoma (GBM) is a malignant tumor with a median survival rate of 15-16 months with
standard care; however, cases of successful treatment offer hope that an enhanced …

There is an emerging understanding of the importance of the vascular system within stem
cell niches. Here, we examine whether neural stem cells (NSCs) in the adult subventricular …

The persistence of an active subventricular zone neural stem cell niche in the adult
mammalian forebrain supports its continued role in the production of new neurons and in …

Telocytes (TCs) are a recently identified type of interstitial cells present in a wide variety of
organs in humans and mammals (www. telocytes. com). They are characterized by a small …

Using a mouse model of ependymoma—a chemoresistant brain tumor—we combined
multicell high-throughput screening (HTS), kinome-wide binding assays, and in vivo efficacy …

Abstract The Murphy Roths Large (MRL/MpJ) mice provide unique insights into wound
repair and regeneration. These mice and the closely related MRL/MpJ-Fas lpr/J and Large …

Background Cerebral vasospasm (CV) can contribute to significant morbidity in
subarachnoid hemorrhage (SAH) patients. A key unknown is how CV induction is triggered …

INSM1 is a zinc‐finger protein expressed in the developing nervous system and pancreas
as well as in medulloblastomas and neuroendocrine tumors. With in situ hybridization …

Introduction The unbound brain extracelullar fluid (brainECF) to plasma steady state
partition coefficient, Kp, uu, BBB, values provide steady-state information on the extent of …