A current view of the mammalian aquaglyceroporins

A Rojek, J Praetorius, J Frøkiaer, S Nielsen… - Annu. Rev …, 2008 - annualreviews.org
The discovery of aquaporin water channels by Agre and coworkers answered a long-
standing biophysical question of how the majority of water crosses biological membranes …

Function of aquaporins in female and male reproductive systems

HF Huang, RH He, CC Sun, Y Zhang… - Human reproduction …, 2006 - academic.oup.com
The flow of water and some other small molecules across cell membranes is important in
many of the processes underlying reproduction. The fluid movement is strongly associated …

Insulin-and leptin-mediated control of aquaglyceroporins in human adipocytes and hepatocytes is mediated via the PI3K/Akt/mTOR signaling cascade

A Rodríguez, V Catalan… - The Journal of …, 2011 - academic.oup.com
Objective: Glycerol constitutes an important metabolite for the control of lipid accumulation
and glucose homeostasis. The impact of obesity and obesity-associated type 2 diabetes as …

Regulation of brain aquaporins

M Zelenina - Neurochemistry international, 2010 - Elsevier
Three aquaporins are expressed in the brain. AQP4, the predominant brain water channel,
is expressed in astrocyte endfeet facing brain capillaries, perisynaptic spaces, and nodes of …

Roles of steroid hormones in oviductal function

BE Barton, GG Herrera, P Anamthathmakula… - …, 2020 - rep.bioscientifica.com
The oviduct (known as the fallopian tube in humans) is the site for fertilization and pre-
implantation embryo development. Female steroid hormones, estrogen and progesterone …

Female reproductive tract fluids: composition, mechanism of formation and potential role in the developmental origins of health and disease

HJ Leese, SA Hugentobler, SM Gray… - Reproduction …, 2007 - CSIRO Publishing
The oviduct and uterus provide the environments for the earliest stages of mammalian
embryo development. However, little is known about the mechanisms that underlie the …

The multifaceted role of aquaporin-9 in health and its potential as a clinical biomarker

IV da Silva, S Garra, G Calamita, G Soveral - Biomolecules, 2022 - mdpi.com
Aquaporins (AQPs) are transmembrane channels essential for water, energy, and redox
homeostasis, with proven involvement in a variety of pathophysiological conditions such as …

Relationship of expression of aquaglyceroporin 9 with arsenic uptake and sensitivity in leukemia cells

J Leung, A Pang, WH Yuen, YL Kwong, EWC Tse - Blood, 2007 - ashpublications.org
Abstract Arsenic trioxide (As2O3) is highly efficacious in acute promyelocytic leukemia
(APL). Aquaglyceroporin 9 (AQP9) is a transmembrane protein that may be involved in …

[HTML][HTML] Aquaporins and (in) fertility: More than just water transport

JC Ribeiro, MG Alves, M Yeste, YS Cho… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Aquaporins (AQPs) are a family of channel proteins that facilitate the transport of water and
small solutes across biological membranes. They are widely distributed throughout the …

Reduced hepatic aquaporin-9 and glycerol permeability are related to insulin resistance in non-alcoholic fatty liver disease

A Rodríguez, P Gena, L Méndez-Giménez… - International journal of …, 2014 - nature.com
Results: AQP9 was the most abundantly (P< 0.0001) expressed aquaglyceroporin in human
liver (AQP9>>> AQP3> AQP7> AQP10). Obese patients with T2D showed increased plasma …