Senescence in the ageing skin: a new focus on m TORC 1 and the lysosome

P Smith, B Carroll - The FEBS Journal, 2024 - Wiley Online Library
Ageing is defined as the progressive loss of tissue function and regenerative capacity and is
caused by both intrinsic factors ie the natural accumulation of damage, and extrinsic factors …

Decoding the impact of ageing and environment stressors on skin cell communication

AVS Faria, SS Andrade - Biogerontology, 2025 - Springer
The integumentary system serves as a crucial protective barrier and is subject to complex
signaling pathways that regulate its physiological functions. As the body's first line of …

Strategies to Make Human Skin Models based on Cellular Senescence for Ageing Research

Z Shakel, SAC Lima, S Reis - Ageing Research Reviews, 2024 - Elsevier
Human skin ageing is closely related to the ageing of the whole organism, and it's a
continuous multisided process that is influenced not only by genetic and physiological …

Research Progress in Skin Aging and Immunity

X He, X Gao, W Xie - International Journal of Molecular Sciences, 2024 - mdpi.com
Skin aging is a complex process involving structural and functional changes and is
characterized by a decrease in collagen content, reduced skin thickness, dryness, and the …

[HTML][HTML] Development and Applications of Bambusa stenostachya Leaf Extract in Personal Care Products

HC Liu, CY Hsieh, PW Tsai, TY Chou, SC Yang… - Processes, 2025 - mdpi.com
Concerns about the safety of traditional preservatives in personal care products are driving
interest toward self-preserving alternatives. This study explores the potential of B …

CLCA2: A Potential Guardian against Premature Senescence and Skin Aging

L Guerrero-Navarro, I Martic, C Ploner, P Jansen-Dürr… - Biomedicines, 2024 - mdpi.com
Cellular senescence, a state of irreversible growth arrest, is implicated in various age-
related pathologies, including skin aging. In this study, we investigated the role of CLCA2, a …

Artichoke Leaf Extract Effectiveness on the Skin Aging Exposome: Efficacy and Safety Results of a Split-Face Study

G Roveda, E Cestone, F De Gennaro, A Poggi… - Cosmetics, 2024 - mdpi.com
The skin is a barrier organ subjected to lifelong exposure to internal and external factors
influencing both its biological response and appearance. A randomized split-face study was …

[HTML][HTML] Omics-Based Interaction Analysis Reveals Interplay of Chemical Pollutant (Ozone) and Photoradiation (UVSSR) Stressors in Skin Damage

H Zhang, Y Dong, X Xiao, X Cui, X Gu - Biology, 2025 - mdpi.com
The skin acts as the first line of defense against various environmental stressors, such as
solar ultraviolet radiation, visible light, pollution particles and ozone. Simultaneous exposure …

Evaluating the Impact of Oleocanthal and Oleacein on Skin Aging: Results of a Randomized Clinical Study

SP Nisticò, ME Greco, S Amato, L Bennardo, E Zappia… - Medicina, 2024 - mdpi.com
The prevalence of skin aging and the request for effective treatments have driven
dermatological research towards natural solutions. This study investigates the anti-aging …

Butin Protects Keratinocytes From Particulate Matter 2.5 and Ultraviolet B‐Mediated Damages

PDSM Fernando, MJ Piao, KA Kang… - Photodermatology …, 2024 - Wiley Online Library
Background Butin is a naturally occurring compound with a wide range of medicinal
properties, including anti‐inflammatory, anti‐arthritic, and antioxidant properties. Particulate …