Construction and characterization of a novel Tenofovir-loaded PEGylated niosome conjugated with TAT peptide for evaluation of its cytotoxicity and anti-HIV effects

MS Yadavar-Nikravesh, S Ahmadi, A Milani… - Advanced Powder …, 2021 - Elsevier
In recent years, nanocarriers have become potent drug delivery system candidates,
especially in anti-HIV therapies. Meanwhile, using cell-penetrating peptides such as TAT for …

Synthesis, biological evaluation, and molecular modeling studies of new 1,3,4-oxadiazole- and 1,3,4-thiadiazole-substituted 4-oxo-4H-pyrido[1,2-a]pyrimidines as …

Z Hajimahdi, A Zarghi, R Zabihollahi… - Medicinal Chemistry …, 2013 - Springer
A new series of 4-oxo-4 H-pyrido [1, 2-a] pyrimidine derivatives containing 1, 3, 4-oxadiazole
and 1, 3, 4-thiadiazole rings as a part of the metal chelation motif were synthesized and …

[HTML][HTML] Inhibitory activity of Avicennia marina, a medicinal plant in Persian folk medicine, against HIV and HSV

R Namazi, R Zabihollahi, M Behbahani… - Iranian journal of …, 2013 - ncbi.nlm.nih.gov
Avicennia marina (Avicenniaceae) is a species of mangrove tree used for treatment of small
pox lesions in Persian folk medicine. The antiviral activity of methanol, ethanol, water …

Design, synthesis, and docking studies of new 2-benzoxazolinone derivatives as anti-HIV-1 agents

M Safakish, Z Hajimahdi, R Zabihollahi… - Medicinal Chemistry …, 2017 - Springer
A new class of 2-benzoxazolinone derivatives was designed and synthesized for its anti-
human immunodeficiency virus-1 activity. The benzoxazolinone scaffold could be replaced …

Novel quinolone-3-carboxylic acid derivatives as anti-HIV-1 agents: design, synthesis, and biological activities

Z Hajimahdi, R Zabihollahi, MR Aghasadeghi… - Medicinal Chemistry …, 2016 - Springer
A new series of quinolone-3-carboxylic acids featuring different hydrophobic groups at N-1,
C-2, C-7, and C-8 positions were synthesized and evaluated for their activity against single …

Inhibition of HIV and HSV infection by vaginal lactobacilli in vitro and in vivo

R Zabihollahi, E Motevaseli, SM Sadat… - DARU Journal of …, 2012 - Springer
Background and the purpose of the study The cervico-vaginal mucosa which is populated
with microflora (mostly includes lactobacilli) is the portal of entry for sexually transmitted …

Design, synthesis, molecular modeling and anti-HIV assay of novel quinazolinone incorporated coumarin derivatives

M Safakish, Z Hajimahdi, MR Aghasadeghi… - Current HIV …, 2020 - ingentaconnect.com
Background: The emergence of drug-resistant viral strains has created the need for the
development of novel anti-HIV agents with a diverse structure that targets key enzymes in …

Synthesis and evaluation of antiviral activities of novel sonochemical silver nanorods against HIV and HSV viruses

M Etemadzade, A Ghamarypour, R Zabihollahi… - Asian Pacific Journal of …, 2016 - Elsevier
Objective To evaluate the effect of novel sonochemical silver nanorods on HIV and herpes
simplex virus type 1 (HSV-1) viruses in human cervical cancer HeLa cells. Methods The …

Application of outer membrane vesicle of Neisseria meningitidis serogroup B as a new adjuvant to induce strongly Th1-oriented responses against HIV-1

M Reza Aghasadeghi, A Sharifat Salmani… - Current HIV …, 2011 - ingentaconnect.com
Despite the worldwide efforts made in the field of HIV vaccine development, an efficient
AIDS vaccine strategy is still vague. Virus-like particles (VLPs) are one of the introduced …

Platelet microparticles: An effective delivery system for anti-viral drugs

S Soleymani, F Yari, A Bolhassani… - Journal of Drug Delivery …, 2019 - Elsevier
Platelet microparticles are the most frequent bloodstream microparticles (∼ 70–90%) which
act as a vector for delivery of mRNA, miRNA and signaling proteins under physiological …