Osteoporosis is a progressive skeletal disease characterized by decreased bone mass and
degraded bone microstructure, which leads to increased bone fragility and risks of bone …

Mechanobiology has underpinned many scientific advances in understanding how
biophysical and biomechanical cues regulate cell behavior by identifying mechanosensitive …

Aim: To determine whether fluid flow-induced shear stress affects the differentiation of bone
marrow-derived human mesenchymal stem cells (hMSCs) into osteogenic cells. Materials & …

Polyurethane (PU) is a promising polymer to support bone–matrix producing cells due to its
durability and mechanical resistance. In this study two types of medical grade poly-ether …

Mesenchymal stem cells (MSCs) have the potential to replace or restore the function of
damaged tissues and offer much promise in the successful application of tissue engineering …

The present study involves the development of citric acid-cross-linked carboxymethyl
cellulose (C3CA) scaffolds by a freeze-drying process. Scaffolds were fabricated at different …

Treatment of bone defects remains a challenge in the clinic. Artificial bone grafts are the
most promising alternative to autologous bone grafting. However, one of the limiting factors …

Mechanical boundary conditions critically influence the bone healing process. In this
context, previous in vitro studies have demonstrated that cyclic mechanical compression …

Biomaterials-based three-dimensional scaffolds are being extensively investigated in bone
tissue engineering. A potential scaffold should be osteoconductive, osteoinductive, and …

Despite refinements of medical and surgical therapies, heart failure remains a fatal disease.
Myocardial infarction is the most common cause of heart failure, and only palliative …