The global health emergency generated by coronavirus disease 2019 (COVID-19) has
prompted the search for preventive and therapeutic treatments for its pathogen, the severe …

Differential scanning calorimetry (DSC) is an analytical technique that measures the molar
heat capacity of samples as a function of temperature. In the case of protein samples, DSC …

This review focuses on selected applications of the separation and analysis of peptides and
proteins published during the period of 1997-1998. Specific topic areas covered include …

The ninth type III module of murine fibronectin was expressed in E. coli and folded into a
compact homogeneous monomer whose unfolding and refolding were then investigated by …

Endocrine diagnostic tests are dependent on the molecular characteristics of protein
hormones, a property that is also intimately tied to function. The structure–function …

Many therapeutic proteins require storage at room temperature for extended periods of time.
This can lead to aggregation and loss of function. Cyclodextrins (CDs) have been shown to …

Due to its involvement in skin maintenance and repair, topical administration of recombinant
human growth hormone (rhGH) is an interesting strategy for therapeutic purposes. We have …

A61K47/50—Medicinal preparations characterised by the non-active ingredients used, eg
carriers or inert additives; Targeting or modifying agents chemically bound to the active …

Molecular dynamics is here used to elucidate the mechanism of protein stabilization by
carbohydrates and other additives during freezing. More specifically, we used molecular …

Cytoplasmic dynein is a multisubunit ATPase that transforms chemical energy into motion
along microtubules. LC8, a 10 kDa light chain subunit of the dynein complex, is highly …