The demand for high-quality milk is increasing worldwide. The efficiency of milk synthesis
can be improved by taking advantage of the accumulated knowledge of the transcriptional …

The mammary gland is a unique organ with the ability to undergo repeated cyclic changes
throughout the life of mammals. Among domesticated livestock species, ruminants (cattle …

The dynamic impact approach (DIA) represents an alternative to overrepresentation analysis
(ORA) for functional analysis of time-course experiments or those involving multiple …

Background Cow milk is a complex bioactive fluid consumed by humans beyond infancy.
Even though the chemical and physical properties of cow milk are well characterized, very …

The objective of this study was to examine five different sources of RNA, namely mammary
gland tissue (MGT), milk somatic cells (SC), laser microdissected mammary epithelial cells …

Lactation, an important characteristic of mammalian reproduction, has evolved by exploiting
a diversity of strategies across mammals. Comparative genomics and transcriptomics …

Glucose is the major precursor of lactose, which is synthesized in Golgi vesicles of
mammary secretory alveolar epithelial cells during lactation. Glucose is taken up by …

High-throughput sequencing of RNA (RNA-Seq) was developed primarily to analyze global
gene expression in different tissues. However, it also is an efficient way to discover coding …

Abstract Background Recently, RNA sequencing (RNA-seq) has rapidly emerged as a major
transcriptome profiling system. Elucidation of the bovine mammary gland transcriptome by …

The objective of this study was to investigate the transcriptional regulation of lipid synthesis
by sterol regulatory element binding protein-1 (SREBP-1) in bovine mammary epithelial …