Hypertension is a frequent, chronic, age-related disorder, which often entails debilitating
cardiovascular and renal complications. Blood pressure is usually noted in combination with …

Epidemiological, migration, intervention, and genetic studies in humans and animals
provide very strong evidence of a causal link between high salt intake and high blood …

Endogenous cardiotonic steroids (CTS), also called digitalis-like factors, have been
postulated to play important roles in health and disease for nearly half a century. Recent …

Increasingly, primary hypertension is being considered a syndrome and not a disease, with
the individual causes (diseases) having a common sign—an elevated blood pressure. To …

Background Abnormalities in renal sodium transport may be involved in hypertension.
Adducin, an α/β heterodimeric protein found in the renal tubule is thought to regulate ion …

В книге представлены современные данные об этиологии и механизмах развития
артериальной гипертензии при сахарном диабете типа 1 и типа 2, о роли …

Blood pressure is a quantitative trait that has a strong genetic component in humans and
rats. Several selectively bred strains of rats with divergent blood pressures serve as an …

Cnidarians are among the simplest extant animals; however EST analyses reveal that they
have a remarkably high level of genetic complexity. In this article, we show that the full …

In this review, we attempt to outline the age-dependent interactions of principal systems
controlling the structure and function of the cardiovascular system in immature rats …

Compelling evidence for the inherited nature of essential hypertension has led to extensive
research in rats and humans. Rats have served as the primary model for research on the …