Serology as a tool to assess infectious disease landscapes and guide public health policy

AH Haselbeck, J Im, K Prifti, F Marks, M Holm… - Pathogens, 2022 - mdpi.com
Understanding the local burden and epidemiology of infectious diseases is crucial to guide
public health policy and prioritize interventions. Typically, infectious disease surveillance …

Vibrio cholerae at the Intersection of Immunity and the Microbiome

AA Weil, RL Becker, JB Harris - MSphere, 2019 - Am Soc Microbiol
Vibrio cholerae is a noninvasive pathogen that colonizes the small intestine and produces
cholera toxin, causing severe secretory diarrhea. Cholera results in long lasting immunity …

Multiplex assays for the identification of serological signatures of SARS-CoV-2 infection: an antibody-based diagnostic and machine learning study

J Rosado, S Pelleau, C Cockram, SH Merkling… - The Lancet …, 2021 - thelancet.com
Background Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
induces an antibody response targeting multiple antigens that changes over time. This study …

A subset of follicular helper-like MAIT cells can provide B cell help and support antibody production in the mucosa

O Jensen, S Trivedi, JD Meier, KC Fairfax, JS Hale… - Science …, 2022 - science.org
Mucosal-associated invariant T (MAIT) cells are innate-like T lymphocytes that aid in
protection against bacterial pathogens at mucosal surfaces through the release of …

[HTML][HTML] Seroepidemiologic study designs for determining SARS-COV-2 transmission and immunity

H Clapham, J Hay, I Routledge… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
Serologic studies are crucial for clarifying dynamics of the coronavirus disease pandemic.
Past work on serologic studies (eg, during influenza pandemics) has made relevant …

Clinical surveillance systems obscure the true cholera infection burden in an endemic region

ST Hegde, AI Khan, J Perez-Saez, II Khan, JD Hulse… - Nature medicine, 2024 - nature.com
Our understanding of cholera transmission and burden largely relies on clinic-based
surveillance, which can obscure trends, bias burden estimates and limit the impact of …

Kinetics of the severe acute respiratory syndrome coronavirus 2 antibody response and serological estimation of time since infection

S Pelleau, T Woudenberg, J Rosado… - The Journal of …, 2021 - academic.oup.com
Background Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
induces a complex antibody response that varies by orders of magnitude between …

Mathematical models for cholera dynamics—A review

J Wang - Microorganisms, 2022 - mdpi.com
Cholera remains a significant public health burden in many countries and regions of the
world, highlighting the need for a deeper understanding of the mechanisms associated with …

Emerging concepts in cholera vaccine design

B Sit, B Fakoya, MK Waldor - Annual Review of Microbiology, 2022 - annualreviews.org
Cholera is a severe diarrheal disease caused by the bacterium Vibrio cholerae and
constitutes a significant public health threat in many areas of the world. V. cholerae infection …

Effectiveness of one dose of killed oral cholera vaccine in an endemic community in the Democratic Republic of the Congo: a matched case-control study

EB Malembaka, PM Bugeme, C Hutchins… - The Lancet Infectious …, 2024 - thelancet.com
Background A global shortage of cholera vaccines has increased the use of single-dose
regimens, rather than the standard two-dose regimen. There is sparse evidence on single …