Nanocarrier hydrodynamics and binding in targeted drug delivery: challenges in numerical modeling and experimental validation

PS Ayyaswamy, V Muzykantov… - Journal of …, 2013 - asmedigitalcollection.asme.org
This review discusses current progress and future challenges in the numerical modeling of
targeted drug delivery using functionalized nanocarriers (NC). Antibody coated nanocarriers …

Molecular systems biology of ErbB1 signaling: bridging the gap through multiscale modeling and high-performance computing

AJ Shih, J Purvis, R Radhakrishnan - Molecular BioSystems, 2008 - pubs.rsc.org
The complexity in intracellular signaling mechanisms relevant for the conquest of many
diseases resides at different levels of organization with scales ranging from the subatomic …

[HTML][HTML] Cancer cell: linking oncogenic signaling to molecular structure

JE Purvis, AJ Shih, Y Liu… - Chapman & Hall/CRC …, 2011 - ncbi.nlm.nih.gov
A multiscale strategy is presented for constructing models of intracellular signaling networks
in which the oncogenic behavior of the network is encoded through alternate …

Linking Oncogenic Signaling to Molecular Structure

JE Purvis, AJ Shih, Y Liu… - Multiscale Cancer …, 2010 - api.taylorfrancis.com
▪ Cancer Cell: Linking Oncogenic Signaling to Molecular Structure Page 1 31 CHAPTER 2
Cancer Cell Linking Oncogenic Signaling to Molecular Structure Jeremy E. Purvis, Andrew J …

[PDF][PDF] Molecular BioSystems

R Radhakrishnan - Mol. BioSyst, 2008 - seas.upenn.edu
The complexity in intracellular signaling mechanisms relevant for the conquest of many
diseases resides at different levels of organization with scales ranging from the subatomic …