Toxicological property of acetaminophen: the dark side of a safe antipyretic/analgesic drug?

Y Ishitsuka, Y Kondo, D Kadowaki - Biological and pharmaceutical …, 2020 - jstage.jst.go.jp
Abstract Acetaminophen (paracetamol, N-acetyl-p-aminophenol; APAP) is the most popular
analgesic/antipyretic agent in the world. APAP has been regarded as a safer drug compared …

[HTML][HTML] Paracetamol inhibits Ca2+ permeant ion channels and Ca2+ sensitization resulting in relaxation of precontracted airway smooth muscle

YY Chen, MF Yu, XX Zhao, J Shen, YB Peng… - Journal of …, 2020 - Elsevier
The purpose of this study was to screen a bronchodilator from old drugs and elucidate the
underlying mechanism. Paracetamol (acetaminophen) is a widely used analgesic and …

Acetaminophen is both bronchodilatory and bronchoprotective in human precision cut lung slice airways

JL Kennedy, RC Kurten, S McCullough, RA Panettieri… - Xenobiotica, 2019 - Taylor & Francis
Epidemiologic studies have demonstrated an association between acetaminophen (APAP)
use and the development of asthma symptoms. However, few studies have examined …

[PDF][PDF] GEBE RATLARDA GEBELĠK ESNASINDA TEKRARLAYAN DOZLARDA PARASETAMOL UYGULAMASININ DOĞACAK RATLARIN AKCĠĞER, BÖBREK VE …

DRNT ÖZTERLEMEZ, DRN ĠNAN - avesis.gazi.edu.tr
D Araştırma veya pazarlama deneyimlerinden veya insanlardan yapılan çalışmalardan elde
edilen olumsuz reaksiyon verilerine dayanarak insan fetal riskine ilişkin olumlu kanıtlar …

Gebe ratlarda gebelik esnasında tekrarlayan dozlarda parasetamol uygulamasının doğacak ratların akciğer, böbrek ve karaciğer dokuları üzerine etkileri.

N Türk Özterlemez - acikbilim.yok.gov.tr
Dünyada yaygın olarak kullanılan analjezik ve antipiretiklerin başında Parasetamol
gelmektedir. Gebelikte ise en sık kullanılan anealjezik ve antipiretik ajandır. Parasetamolün …

Modulation of Respiratory Tract Responses by Acetaminophen

GJ Smith - 2015 - digitalcommons.lib.uconn.edu
The prevalence of asthma is increasing, and the cause (s) of this increase are unknown. The
etiology of asthma is complex and includes both genetic, developmental, and environmental …