The role of stereotactic ablative body radiotherapy in renal cell carcinoma

M Ali, J Mooi, N Lawrentschuk, RR McKay, R Hannan… - European urology, 2022 - Elsevier
Context Stereotactic ablative body radiotherapy (SABR) is an emerging treatment modality
for primary and metastatic renal cell carcinoma (RCC). Objective To review and summarise …

[HTML][HTML] Effective strategies to enhance the diagnosis and treatment of RCC: The application of biocompatible materials

J Li, P Luo, S Liu, M Fu, A Lin, Y Liu, Z He, K Qiao… - Materials Today Bio, 2024 - Elsevier
Renal cell carcinoma (RCC) is recognized as one of the three primary malignant tumors
affecting the urinary system, posing a significant risk to human health and life. Despite …

TLR3 activation enhances abscopal effect of radiotherapy in HCC by promoting tumor ferroptosis

L Qiu, H Ji, K Wang, W Liu, Q Huang, X Pan… - EMBO Molecular …, 2024 - embopress.org
Radiotherapy (RT) has been reported to induce abscopal effect in advanced hepatocellular
carcinoma (HCC), but such phenomenon was only observed in sporadic cases. Here, we …

Intratumoral Injectable Redox‐Responsive Immune Niche Improves the Abscopal Effect in Radiotherapy

KM Au, JS Swinnea, AZ Wang - Advanced Materials, 2024 - Wiley Online Library
Radiotherapy (XRT) is often utilized to improve the immune checkpoint blockade response
in cancer management. Such combination treatment can enhance the abscopal effect …

Radiation therapy regulates TCF-1 to maintain CD8+ T cell stemness and promotes anti-tumor immunotherapy

B Wang, J Hu, J Zhang, L Zhao - International Immunopharmacology, 2022 - Elsevier
Radiotherapy is a very effective cancer treatment, mainly through inducing DNA damage of
cancer cells. Meanwhile, there is evidence that irradiation can also mobilize tumor-specific …

[HTML][HTML] NeoAdjuvant pembrolizumab and STEreotactic radiotherapy prior to nephrectomy for renal cell carcinoma (NAPSTER): A phase II randomised clinical trial

M Ali, S Wood, D Pryor, D Moon, M Bressel… - Contemporary Clinical …, 2023 - Elsevier
Background Surgery remains the standard of care for localised renal cell carcinoma (RCC).
Nevertheless, nearly 50% of patients with high-risk disease experience relapse after …

First-line immune checkpoint inhibitor combinations in metastatic renal cell carcinoma: where are we going, where have we been?

JJ Adashek, JJ Breunig, E Posadas, NA Bhowmick… - Drugs, 2022 - Springer
The combination of targeted therapy and immunotherapy in the treatment of metastatic renal
cell carcinoma (mRCC) has significantly improved outcomes for many patients. There are …

Organoids as Sophisticated Tools for Renal Cancer Research: Extensive Applications and Promising Prospects

J Huang, X Wang, S Ge, X Lu, C Sun - Cellular and Molecular …, 2024 - Springer
Background Kidney cancer is a significant global health problem that affects nearly 1 in 25 of
cancer patients. Prevalence, morbidity and mortality data associated with kidney cancer …

Incorporating Stereotactic Ablative Radiotherapy into the Multidisciplinary Management of Renal Cell Carcinoma

RK Raj, R Upadhyay, SJ Wang, EA Singer, S Dason - Current Oncology, 2023 - mdpi.com
Stereotactic ablative radiotherapy (SABR) has challenged the conventional wisdom
surrounding the radioresistance of renal cell carcinoma (RCC). In the past decade, there has …

Phase II trial of sipuleucel-T and stereotactic ablative body radiation for patients with metastatic castrate-resistant prostate cancer

R Hannan, MJ Dohopolski, LM Pop, S Mannala… - Biomedicines, 2022 - mdpi.com
(1) We hypothesized that adding concurrent stereotactic ablative radiotherapy (SAbR) would
increase the time to progression in patients with metastatic castrate-resistant prostate cancer …