Defining polypharmacy in the elderly: a systematic review protocol

SS Mortazavi, M Shati, A Keshtkar, SK Malakouti… - BMJ open, 2016 - bmjopen.bmj.com
Introduction Ageing—along with its associated physiological and pathological changes—
places individuals at a higher risk of multimorbidity and treatment-related complications …

Polypharmacy and potentially inappropriate medication use in geriatric oncology

M Sharma, KP Loh, G Nightingale, SG Mohile… - Journal of geriatric …, 2016 - Elsevier
Polypharmacy is a highly prevalent problem in older persons, and is challenging to assess
and improve due to variations in definitions of the problem and the heterogeneous methods …

[HTML][HTML] Risk factors for hospital readmission in older adults within 30 days of discharge–a comparative retrospective study

M Glans, A Kragh Ekstam, U Jakobsson, Å Bondesson… - BMC geriatrics, 2020 - Springer
Background The area of hospital readmission in older adults within 30 days of discharge is
extensively researched but few studies look at the whole process. In this study we …

[HTML][HTML] Stroke, multimorbidity and polypharmacy in a nationally representative sample of 1,424,378 patients in Scotland: implications for treatment burden

KI Gallacher, GD Batty, G McLean, SW Mercer… - BMC medicine, 2014 - Springer
Background The prevalence of multimorbidity (the presence of two or more long-term
conditions) is rising internationally. Multimorbidity affects patients by increasing their burden …

Polypharmacy: a general review of definitions, descriptions and determinants

J Guillot, S Maumus-Robert, J Bezin - Therapies, 2020 - Elsevier
Polypharmacy is considered as the administration of many drugs. It is a major public health
concern, which is growing worldwide. The identification of polypharmacy relies on drug …

Routine deprescribing of chronic medications to combat polypharmacy

D Garfinkel, B Ilhan, G Bahat - Therapeutic advances in drug …, 2015 - journals.sagepub.com
The positive benefit–risk ratio of most drugs is decreasing in correlation to very old age, the
extent of comorbidity, dementia, frailty and limited life expectancy (VOCODFLEX). First, we …

Social engagement and allostatic load mediate between adverse childhood experiences and multimorbidity in mid to late adulthood: the Canadian Longitudinal Study …

L Atkinson, D Joshi, P Raina, LE Griffith… - Psychological …, 2023 - cambridge.org
Background Adverse childhood experiences (ACEs) are associated with multimorbidity in
adulthood. This link may be mediated by psychosocial and biological factors, but evidence is …

[HTML][HTML] Prevalence and risk factors of drug-related hospitalizations in multimorbid patients admitted to an internal medicine ward

M Lea, M Mowe, L Mathiesen, K Kvernrød, E Skovlund… - PloS one, 2019 - journals.plos.org
Background Knowledge of risk factors for drug-related hospitalizations (DRHs) is limited.
Aim To examine the prevalence of DRHs and the relationships between DRHs and various …

Adverse drug events in patients with advanced chronic conditions who have a prognosis of limited life expectancy at hospital admission

D Sevilla-Sanchez, N Molist-Brunet… - European journal of …, 2017 - Springer
Abstract Purpose Adverse drug events (ADEs) lead to adverse clinical outcomes such as
hospitalization. There is little information about the characteristics of ADEs in patients with …

[HTML][HTML] Malnutrition and depression as predictors for 30-day unplanned readmission in older patient: a prospective cohort study to develop 7-point scoring system

I Fitriana, S Setiati, EW Rizal, R Istanti, I Rinaldi… - BMC geriatrics, 2021 - Springer
Background Readmission is related to high cost, high burden, and high risk for mortality in
geriatric patients. A scoring system can be developed to predict the readmission of older …