As one of the most important mineral nutrient elements, potassium (K+) participates in many
plant physiological processes and determines the yield and quality of crop production. In this …

The human genome encodes 40 voltage-gated K+ channels (KV), which are involved in
diverse physiological processes ranging from repolarization of neuronal and cardiac action …

The intrinsic electrical properties and the synaptic input-output relationships of neurons are
governed by the action of voltage-dependent ion channels. The localization of specific …

Potassium channels are particularly important in determining the shape and duration of the
action potential, controlling the membrane potential, modulating hormone secretion …

Plant plasma membrane intrinsic proteins (PIPs) cluster in two evolutionary subgroups, PIP1
and PIP2, with different aquaporin activities when expressed in Xenopus oocytes. Maize …

Zea mays plasma membrane intrinsic proteins (ZmPIPs) fall into two groups, ZmPIP1s and
ZmPIP2s, that exhibit different water channel activities when expressed in Xenopus oocytes …

Exome and targeted sequencing have revolutionized clinical diagnosis. This has been
particularly striking in epilepsy and neurodevelopmental disorders, for which new genes or …

Insulin secretion from pancreatic islet beta cells is acutely regulated by a complex interplay
of metabolic and electrogenic events. The electrogenic mechanism regulating insulin …

Cation levels within the cytosol are coordinated by a network of transporters. Here, we
examine the functional roles of calcium exchanger 1 (CAX1), a vacuolar H+/Ca2+ …

Hereditary cone disorders (CDs) are characterized by defects of the cone photoreceptors or
retinal pigment epithelium underlying the macula, and include achromatopsia (ACHM), cone …