Intra-articular drug delivery has a number of advantages over systemic administration;
however, for the past 20 years, intra-articular treatment options for the management of knee …

The purpose of this article is to provide a synopsis of the current medical understanding of
knee osteoarthritis. We describe the prevalence, causes and associated risk factors …

Introduction Platelet-rich plasma (PRP) is able to modulate the joint environment by
reducing the inflammatory distress and promoting tissue anabolism. Therefore, it has gained …

Purpose To use meta-analysis techniques to evaluate the efficacy and safety of platelet-rich
plasma (PRP) injections for the treatment knee of osteoarthritis (OA). Methods We performed …

Background Quite a few randomized controlled trials (RCTs) investigating the efficacy of
platelet-rich plasma (PRP) for treatment of knee osteoarthritis (OA) have been recently …

Subtalar osteoarthritis (STOA) is often secondary to chronic ankle sprains, which seriously
affects the quality of life of patients. Due to its etiology and pathogenesis was not studied …

Background: Leukocyte-poor platelet-rich plasma (LP-PRP) is hypothesized to be more
suitable for intra-articular injection than leukocyte-rich PRP (LR-PRP) in the treatment of …

Abstract Purpose of Review Knee and hip osteoarthritis (OA) are major public health
problems worldwide causing pain, disability and impaired quality of life. This narrative paper …

Purpose The aims of this study were (1) to perform a systematic review of meta-analyses
evaluating platelet-rich plasma (PRP) injection in the treatment of knee joint cartilage …

PURPOSE: This multicenter, double-blind clinical trial evaluated and compared the efficacy
and safety of PRGF-Endoret (BTI Biotechnology Institute, Vitoria-Gasteiz, Spain), an …