Evolution of exon-intron structure of eukaryotic genes has been a matter of long-standing,
intensive debate. The introns-early concept, later rebranded 'introns first'held that protein …

The origins and importance of spliceosomal introns comprise one of the longest-abiding
mysteries of molecular evolution. Considerable debate remains over several aspects of the …

Around 98% of all transcriptional output in humans is non-coding RNA. RNA-mediated gene
regulation is widespread in higher eukaryotes and complex genetic phenomena like RNA …

Abstract'Out-of-body'experiences (OBEs) are curious, usually brief sensations in which a
person's consciousness seems to become detached from the body and take up a remote …

Eukaryotic phenotypic diversity arises from multitasking of a core proteome of limited size.
Multitasking is routine in computers, as well as in other sophisticated information systems …

RNA metabolism, broadly defined as the compendium of all processes that involve RNA,
including transcription, processing and modification of transcripts, translation, RNA …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Until recently, retention of introns in mature mRNAs has been regarded as a consequence of
mis‐splicing. Intron‐retaining transcripts are thought to be non‐functional because they are …

Abstract'Selfish genetic elements', such as transposons, homing endonucleases, meiotic
drive chromosomes and heritable microorganisms, are common features of eukaryotes …

Prokaryotes constitute a single kingdom, Bacteria, here divided into two new subkingdoms:
Negibacteria, with a cell envelope of two distinct genetic membranes, and Unibacteria …