Understanding of changes in thyroid function and the consequences of thyroid disease
during pregnancy has rapidly grown in the past two decades, and revised American Thyroid …

Thyroid hormones are crucial for the growth and maturation of many target tissues,
especially the brain and skeleton. During critical periods in the first trimester of pregnancy …

Context: Maternal thyroid dysfunction, especially in early pregnancy, may lead to pregnancy
complications and adverse birth outcomes. Few population-based prospective studies have …

Normal physiological changes of pregnancy warrant the need to employ gestation specific
reference ranges for the interpretation of thyroid function tests. Thyroid hormones play …

Background: Establishment of trimester-and assay-specific reference intervals for every
population is recommended. The aim of this study was to establish a trimester-and …

Diagnosis, prognostication, and monitoring of maternal health throughout pregnancy relies
on laboratory testing, including but not limited to key markers of thyroid, hepatic, cardiac …

Thyroid hormones are primarily responsible for regulating the basal metabolic rate but also
make important contributions to reproductive function and fetal development. Both hyper …

Maternal effects are currently acknowledged as important causes of transgenerational
phenotypic variation and a potential mechanism to adapt offspring to predicted …

Background Maternal thyroid hormones' supply is crucial for fetal neurodevelopment;
however, the role of maternal mild thyroid dysfunction is not clear. We aimed to assess the …

While there is agreement that overt maternal hypothyroidism (serum thyroid stimulating
hormone (TSH)> 10 mIU/L) should be treated immediately, the evidence is mixed regarding …