Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …

The endocannabinoid (eCB) system has emerged as a central integrator linking the
perception of external and internal stimuli to distinct neurophysiological and behavioural …

Emotions are “feeling” states and classic physiological emotive responses that are
interpreted based on the history of the organism and the context. Motivation is a persistent …

Exposure to stress is an undeniable, but in most cases surmountable, part of life. However,
in certain individuals, exposure to severe or cumulative stressors can lead to an array of …

Endocannabinoids (eCBs) are a family of lipid molecules that act as key regulators of
synaptic transmission and plasticity. They are synthetized “on demand” following …

The endocannabinoid (eCB) system is one the most ubiquitous signaling systems of the
brain and offers a rich pharmacology including multiple druggable targets. Preclinical …

The endocannabinoid system (ECS), which is composed of the cannabinoid receptors types
1 and 2 (CB1 and CB2) for marijuana's psychoactive ingredient∆ 9-tetrahydrocannabinol (∆ …

Although anecdotal reports suggest that cannabis may be used to alleviate symptoms of
depression, the psychotropic effects and abuse liability of this drug prevent its therapeutic …

The hypothalamic-pituitary-adrenal (HPA) axis regulates the outflow of glucocorticoid
hormones under basal conditions and in response to stress. Within the last decade, a large …

Post-traumatic stress disorder (PTSD) is a common, debilitating condition with limited
treatment options. Extinction of fear memories through prolonged exposure therapy, the …