Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer's disease

AS Ríos, S Oxenford, C Neudorfer, K Butenko… - Nature …, 2022 - nature.com
Deep brain stimulation (DBS) to the fornix is an investigational treatment for patients with
mild Alzheimer's Disease. Outcomes from randomized clinical trials have shown that …

[HTML][HTML] Lead-DBS v3. 0: Mapping deep brain stimulation effects to local anatomy and global networks

C Neudorfer, K Butenko, S Oxenford, N Rajamani… - Neuroimage, 2023 - Elsevier
Following its introduction in 2014 and with support of a broad international community, the
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …

The history of deep brain stimulation

F Cavallieri, E Mulroy, E Moro - Parkinsonism & Related Disorders, 2024 - Elsevier
Deep brain stimulation (DBS) surgery is an established and effective treatment for several
movement disorders (tremor, Parkinson's disease, and dystonia), and is under investigation …

Automated deep brain stimulation programming based on electrode location: a randomised, crossover trial using a data-driven algorithm

J Roediger, TA Dembek, J Achtzehn… - The Lancet Digital …, 2023 - thelancet.com
Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is highly
effective in controlling motor symptoms in patients with Parkinson's disease. However …

Deep brain stimulation for obsessive-compulsive disorder: Optimal stimulation sites

GM Meyer, B Hollunder, N Li, K Butenko, TA Dembek… - Biological …, 2024 - Elsevier
Background Deep brain stimulation (DBS) is a promising treatment option for treatment-
refractory obsessive-compulsive disorder (OCD). Several stimulation targets have been …

StimFit—a data‐driven algorithm for automated deep brain stimulation programming

J Roediger, TA Dembek, G Wenzel… - Movement …, 2022 - Wiley Online Library
Background Finding the optimal deep brain stimulation (DBS) parameters from a multitude
of possible combinations by trial and error is time consuming and requires highly trained …

The role of KCNQ channel activators in management of major depressive disorder

S Meshkat, ATH Kwan, GH Le, S Wong… - Journal of affective …, 2024 - Elsevier
Depression, a complex disorder with significant treatment challenges, necessitates
innovative therapeutic approaches to address its multifaceted nature and enhance treatment …

Functional anatomy of the subthalamic nucleus and the pathophysiology of cardinal features of Parkinson's disease unraveled by focused ultrasound ablation

R Rodriguez-Rojas, JU Máñez-Miró… - Science …, 2024 - science.org
The subthalamic nucleus (STN) modulates basal ganglia output and plays a fundamental
role in the pathophysiology of Parkinson's disease (PD). Blockade/ablation of the STN …

The contribution of subthalamic nucleus deep brain stimulation to the improvement in motor functions and quality of life

I Tödt, B Al‐Fatly, O Granert, AA Kühn… - Movement …, 2022 - Wiley Online Library
Background Subthalamic nucleus deep brain stimulation (STN‐DBS) effectively treats motor
symptoms and quality of life (QoL) of advanced and fluctuating early Parkinson's disease …

[HTML][HTML] Thalamic deep brain stimulation for Tourette Syndrome: A naturalistic trial with brief randomized, double-blinded sham-controlled periods

JC Baldermann, J Kuhn, T Schüller, S Kohl, P Andrade… - Brain Stimulation, 2021 - Elsevier
Background There is still a lack of controlled studies to prove efficacy of thalamic deep brain
stimulation for Tourette's Syndrome. Objectives In this controlled trial, we investigated the …