What is known about the biological activity of fish cytokines is reviewed. Most of the
functional studies performed to date have been in teleost fish, and have focused on the …

Chikungunya virus (CHIKV) is the aetiological agent of the mosquito-borne disease
chikungunya fever, a debilitating arthritic disease that, during the past 7 years, has caused …

Interferons (IFNs) are the hallmark of the vertebrate antiviral system. Two of the three IFN
families identified in higher vertebrates are now known to be important for antiviral defence …

Interferons (IFN s) have been reported in vertebrates from fish to mammals. To date, two
types of IFN s, ie type I and type II IFN s have been reported in a range of fish species in …

Fish type I IFNs are classified into two groups with two (group I) or four (group II) cysteines in
the mature peptide and can be further divided into four subgroups, termed IFN-a,-b,-c, and-d …

We investigated the antiviral activity and gene induction properties of interferon gamma (IFN-
γ) compared to type I IFN (IFNa1) in Atlantic salmon. IFN-γ protected salmon cells against …

Viruses are the most serious pathogenic threat to the production of the main aquacultured
salmonid species the rainbow trout Oncorhynchus mykiss and the Atlantic salmon Salmo …

Abstract Type I IFNs (IFN-I) are cytokines, which play a crucial role in innate and adaptive
immunity against viruses of vertebrates. In essence, IFN-I are induced and secreted upon …

In fish as in mammals, virus infections induce changes in the expression of many host
genes. Studies conducted during the last fifteen years revealed a major contribution of the …

The purpose of this chapter is to provide readers with a general overview of the fish immune
system, including commonalities and particularities in comparison with higher vertebrate …