[HTML][HTML] PDIA3: Structure, functions and its potential role in viral infections

F Mahmood, R Xu, MUN Awan, Y Song, Q Han… - Biomedicine & …, 2021 - Elsevier
The catalysis of disulphide (single bondSsingle bondSsingle bond) bonds is the most
important characteristic of protein disulphide isomerase (PDI) family. Catalysis occurs in the …

Dynamics of MHC-I molecules in the antigen processing and presentation pathway

HV Truong, NG Sgourakis - Current opinion in immunology, 2021 - Elsevier
Highlights•MHC-I molecules exhibit allotype-dependent conformational flexibility, which is
critical for their function.•Peptide-deficient MHC-I adopt distinct groove conformations …

Highly conserved homotrimer cavity formed by the SARS-CoV-2 spike glycoprotein: a novel binding site

U Kalathiya, M Padariya, M Mayordomo… - Journal of clinical …, 2020 - mdpi.com
An important stage in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) life
cycle is the binding of the spike (S) protein to the angiotensin converting enzyme-2 (ACE2) …

PDIA3 expression in glioblastoma modulates macrophage/microglia pro-tumor activation

M Chiavari, GMP Ciotti, F Canonico, F Altieri… - International Journal of …, 2020 - mdpi.com
The glioblastoma (GB) microenvironment includes cells of the innate immune system
identified as glioma-associated microglia/macrophages (GAMs) that are still poorly …

[HTML][HTML] Investigation of the effects of downregulation of jumping translocation breakpoint (JTB) protein expression in MCF7 cells for potential use as a biomarker in …

M Jayathirtha, AN Neagu, D Whitham… - American journal of …, 2022 - ncbi.nlm.nih.gov
MCF7 is a commonly used luminal type A non-invasive/poor-invasive human breast cancer
cell line that does not usually migrate or invade compared with MDA-MB-231 highly …

Cancer Immunology: Immune Escape of Tumors—Expression and Regulation of HLA Class I Molecules and Its Role in Immunotherapies

Y Wang, S Jasinski-Bergner… - Advances in …, 2023 - journals.lww.com
The addition of “avoiding immune destruction” to the hallmarks of cancer demonstrated the
importance of cancer immunology and in particular the role of immune surveillance and …

Viruses, cancer and non-self recognition

M Padariya, U Kalathiya, S Mikac… - Open …, 2021 - royalsocietypublishing.org
Virus–host interactions form an essential part of every aspect of life, and this review is aimed
at looking at the balance between the host and persistent viruses with a focus on the …

Interfaces with structure dynamics of the workhorses from cells revealed through cross-linking mass spectrometry (CLMS)

U Kalathiya, M Padariya, J Faktor, E Coyaud, JA Alfaro… - Biomolecules, 2021 - mdpi.com
The fundamentals of how protein–protein/RNA/DNA interactions influence the structures and
functions of the workhorses from the cells have been well documented in the 20th century. A …

[PDF][PDF] Investigating the effects of protein disulfide isomerase A4 on influenza virus replication in mice and rabbit hemorrhagic disease virus 3C-like protease in cell …

LNWWW Mudiyanselage - 2024 - krex.k-state.edu
Influenza A virus (IAV) infection is one of the important viral infections with a wide host range
including mammals and birds. Protein disulfide isomerases (PDIs) are a diverse family of …

Human dendritic cell subsets in the glioblastoma-associated microenvironment

X Hu, C Jiang, Y Gao, X Xue - Journal of Neuroimmunology, 2023 - Elsevier
Glioblastoma (GBM) is the most aggressive type of glioma (Grade IV). The presence of
cytotoxic T lymphocyte (CTLs) has been associated with improved outcomes in patients with …