Highlights•MHC-I molecules exhibit allotype-dependent conformational flexibility, which is critical for their function.•Peptide-deficient MHC-I adopt distinct groove conformations …
An important stage in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) life cycle is the binding of the spike (S) protein to the angiotensin converting enzyme-2 (ACE2) …
M Chiavari, GMP Ciotti, F Canonico, F Altieri… - International Journal of …, 2020 - mdpi.com
The glioblastoma (GB) microenvironment includes cells of the innate immune system identified as glioma-associated microglia/macrophages (GAMs) that are still poorly …
MCF7 is a commonly used luminal type A non-invasive/poor-invasive human breast cancer cell line that does not usually migrate or invade compared with MDA-MB-231 highly …
Y Wang, S Jasinski-Bergner… - Advances in …, 2023 - journals.lww.com
The addition of “avoiding immune destruction” to the hallmarks of cancer demonstrated the importance of cancer immunology and in particular the role of immune surveillance and …
Virus–host interactions form an essential part of every aspect of life, and this review is aimed at looking at the balance between the host and persistent viruses with a focus on the …
The fundamentals of how protein–protein/RNA/DNA interactions influence the structures and functions of the workhorses from the cells have been well documented in the 20th century. A …
Influenza A virus (IAV) infection is one of the important viral infections with a wide host range including mammals and birds. Protein disulfide isomerases (PDIs) are a diverse family of …
X Hu, C Jiang, Y Gao, X Xue - Journal of Neuroimmunology, 2023 - Elsevier
Glioblastoma (GBM) is the most aggressive type of glioma (Grade IV). The presence of cytotoxic T lymphocyte (CTLs) has been associated with improved outcomes in patients with …