Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …

Osteopontin (OPN) is a multifunctional phosphorylated protein. It is widely involved in solid
tumor progression, such as intensification of macrophage recruitment, inhibition of T-cell …

Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous cancer with limited
understanding of its classification and tumor microenvironment. Here, by performing single …

Background & Aims Fibroblast activation protein (FAP) is expressed on activated fibroblast.
Its role in fibrosis and desmoplasia is controversial, and data on pharmacological FAP …

Osteopontin (OPN) is a multifunctional cytokine that can impact cancer progression.
Therefore, it is crucial to determine the key factors involved in the biological role of OPN for …

The liver is a critical system for metabolism in human beings, which plays an essential role
in an abundance of physiological processes and is vulnerable to endogenous or exogenous …

Articular cartilage is a connective tissue lining the surfaces of synovial joints. When the
cartilage severely wears down, it leads to osteoarthritis (OA), a debilitating disease that …

Senescence is a crucial player in several metabolic disorders and chronic inflammatory
diseases. Recent data prove the involvement of hepatocyte senescence in the development …

Osteopontin characterizes bile duct–associated macrophages a... : Hepatology Osteopontin
characterizes bile duct–associated macrophages and correlates with liver fibrosis severity in …

Transcortical vessels (TCVs) provide effective communication between bone marrow
vascular system and external circulation. Although osteocytes are in close contact with them …