Mechanistic perspectives on anti-aminoacyl-tRNA synthetase syndrome

S Kanaji, W Chen, Y Morodomi, R Shapiro… - Trends in biochemical …, 2023 - cell.com
Antisynthetase syndrome (ASSD) is an autoimmune disease characterized by circulating
autoantibodies against one of eight aminoacyl-tRNA synthetases (aaRSs). Although these …

Issues in autoantibody tests used in the classification criteria for autoimmune rheumatic diseases: the laboratory autoimmunologist's perspective

N Bizzaro, A Mazzoni, T Carbone, L Cinquanta… - Autoimmunity …, 2024 - Elsevier
Classification criteria of autoimmune rheumatic diseases are an important means to define
homogenous groups of patients that can be compared across studies for clinical trials and …

The molecular mechanism underlying dermatomyositis related interstitial lung disease: evidence from bioinformatic analysis and in vivo validation

L Zeng, Y Tang, Y Zhang, L Yue, G Ma, X Ye… - Frontiers in …, 2023 - frontiersin.org
Background Dermatomyositis (DM) is an autoimmune and inflammatory disease that can
affect the lungs, causing interstitial lung diseases (ILD). However, the exact …

Healthcare utilization and unmet needs of patients with antisynthetase syndrome: An international patient survey

M Weiss, MT Holzer, F Muehlensiepen… - Rheumatology …, 2023 - Springer
Antisynthease syndrome (ASSD) is a rare, complex and understudied autoimmune disease.
Internet-based studies can overcome barriers of traditional on-site research and are …

Metagenome-wide association study of gut microbiome features for myositis

Y Li, J Xu, Y Hong, Z Li, X Xing, Y Zhufeng, D Lu… - Clinical …, 2023 - Elsevier
Purpose The clinical relevance and pathogenic role of gut microbiome in both myositis and
its associated interstitial lung disease (ILD) are still unclear. The purpose of this study was to …

Anti‐PL‐12 anti‐synthetase syndrome manifesting with multiple digital ischemia: Case report & review of the literature

SA Doumeth, E Petrinec, H Chaudhary… - Clinical Case …, 2024 - Wiley Online Library
Key Clinical Message Acute digital ischemia is a rare manifestation of anti‐synthetase
syndrome in the absence of Raynaud's phenomenon. A high index of suspicion may result …

Efficacy and safety of JAK inhibitors in connective tissue disease-associated interstitial lung disease

J Wu, C Mei, Z Luo, X Yuan, W Lin, R Du - Chinese Medical Journal, 2025 - mednexus.org
Interstitial lung disease (ILD) encompasses diverse conditions, including fibrotic lung
diseases characterized by cellular proliferation, interstitial inflammation, and fibrosis. ILD …

[HTML][HTML] 抗Jo-1 抗体在特发性炎性肌病临床分层及疾病谱中的意义

李嘉辰, 赖展鸿, 邵苗, 金月波, 高小娟… - Journal of Peking …, 2023 - ncbi.nlm.nih.gov
抗Jo-1抗体在特发性炎性肌病临床分层及疾病谱中的意义- PMC Back to Top Skip to main content
NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

Secondary immune-mediated thrombotic thrombocytopenic purpura in idiopathic inflammatory myopathy: a case-based review

N Ruffer, MT Holzer, LC Bal, S Melderis… - Rheumatology …, 2023 - Springer
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a potentially fatal acquired
thrombotic microangiopathy syndrome that frequently develops in the context of infectious …

Anasarca as the first presentation of anti-synthetase syndrome

J Xiong, T Balakrishnan, W Fong - BMJ Case Reports CP, 2024 - casereports.bmj.com
A woman in her 70s presented with anasarca and exertional dyspnoea. Investigation
showed severe hypoalbuminaemia with no urinary or gastrointestinal protein losses. CT …