The well-known Strecker reaction was first documented by the German chemist Adolph
Strecker (1822À1871) in 1850. 1 It was one of the earliest one-pot and atom economic …

The applications of nitroalkenes in the synthesis of three-to five-membered O, N and S-
heterocycles, including natural products are investigated in this review. These heterocyclic …

In this review, applications of the amide reductive functionalization methodology for the
synthesis and modification of bioactive compounds are covered. A brief summary of the …

Inhibition of carbohydrate processing enzymes is a topic of great interest, as these enzymes
are involved in a plethora of key biochemical events, such as digestion, lysosomal …

As noted inhibitors of glycosidases, iminosugars have enormous therapeutic potential in the
treatment of a number of diseases such as cancer, diabetes, and lysosomal storage …

Inspired by polyhydroxylated pyrrolidine alkaloid natural products, a 18-membered library of
2-aryl polyhydroxylated pyrrolidines has been efficiently prepared in two or three synthetic …

This paper identifies the required configuration and orientation of α-glucosidase inhibitors,
miglitol, α-1-C-butyl-DNJ, and α-1-C-butyl-LAB for binding to ntSI (isomaltase). Molecular …

Pochonicine, the first naturally occurring polyhydroxylated pyrrolizidine containing an
acetamidomethyl group, which was isolated from Pochonia suchlasporia var. suchlasporia …

The Strecker reaction is one of the most attractive methods for the synthesis of α-amino acids
and other bioactive compounds including natural products. The asymmetric Strecker …

A simple method for the synthesis of sugar-derived imines by a Schwartz's reagent reduction
of easily available sugar lactams has been described. A direct addition of nucleophiles to …