Functional connectomics in depression: insights into therapies

Y Chai, YI Sheline, DJ Oathes, NL Balderston… - Trends in Cognitive …, 2023 - cell.com
Depression is a common mental disorder characterized by heterogeneous cognitive and
behavioral symptoms. The emerging research paradigm of functional connectomics has …

The challenges and prospects of brain-based prediction of behaviour

J Wu, J Li, SB Eickhoff, D Scheinost… - Nature Human Behaviour, 2023 - nature.com
Relating individual brain patterns to behaviour is fundamental in system neuroscience.
Recently, the predictive modelling approach has become increasingly popular, largely due …

[HTML][HTML] One size does not fit all: methodological considerations for brain-based predictive modeling in psychiatry

E Dhamala, BTT Yeo, AJ Holmes - Biological Psychiatry, 2023 - Elsevier
Psychiatric illnesses are heterogeneous in nature. No illness manifests in the same way
across individuals, and no two patients with a shared diagnosis exhibit identical symptom …

[HTML][HTML] Proportional intracranial volume correction differentially biases behavioral predictions across neuroanatomical features, sexes, and development

E Dhamala, LQR Ooi, J Chen, R Kong, KM Anderson… - NeuroImage, 2022 - Elsevier
Individual differences in brain anatomy can be used to predict variations in cognitive ability.
Most studies to date have focused on broad population-level trends, but the extent to which …

The prediction of brain activity from connectivity: advances and applications

M Bernstein-Eliav, I Tavor - The Neuroscientist, 2024 - journals.sagepub.com
The human brain is composed of multiple, discrete, functionally specialized regions that are
interconnected to form large-scale distributed networks. Using advanced brain-imaging …

The burden of reliability: How measurement noise limits brain-behaviour predictions

M Gell, SB Eickhoff, A Omidvarnia, V Küppers, KR Patil… - BioRxiv, 2023 - biorxiv.org
Current major efforts in human neuroimaging research aim to understand individual
differences and identify biomarkers for clinical applications. One particularly promising …

[HTML][HTML] Comparison between gradients and parcellations for functional connectivity prediction of behavior

R Kong, YR Tan, N Wulan, LQR Ooi, SR Farahibozorg… - NeuroImage, 2023 - Elsevier
Resting-state functional connectivity (RSFC) is widely used to predict behavioral measures.
To predict behavioral measures, representing RSFC with parcellations and gradients are the …

[HTML][HTML] Relationship between prediction accuracy and feature importance reliability: An empirical and theoretical study

J Chen, LQR Ooi, TWK Tan, S Zhang, J Li, CL Asplund… - NeuroImage, 2023 - Elsevier
There is significant interest in using neuroimaging data to predict behavior. The predictive
models are often interpreted by the computation of feature importance, which quantifies the …

Poverty, Brain Development, and Mental Health: Progress, Challenges, and Paths Forward

CS Monk, FA Hardi - Annual Review of Developmental …, 2023 - annualreviews.org
Poverty is associated with changes in brain development and elevates the risk for
psychopathology in childhood, adolescence, and adulthood. Although the field is rapidly …

[HTML][HTML] Brain-based predictions of psychiatric illness–linked behaviors across the sexes

E Dhamala, LQR Ooi, J Chen, JA Ricard, E Berkeley… - Biological …, 2023 - Elsevier
Background Individual differences in functional brain connectivity can be used to predict
both the presence of psychiatric illness and variability in associated behaviors. However …