Virulence factors of Paracoccidioides brasiliensis as therapeutic targets: a review

LA Santos, JC Grisolia, E Burger… - Antonie Van …, 2020 - Springer
Paracoccidiodomycosis (PCM) is a systemic mycosis caused by the fungus
Paracoccidioides brasiliensis and Paracoccidioides lutzii. The disease requires long and …

[HTML][HTML] Diagnosis of Human Endemic Mycoses Caused by Thermally Dimorphic Fungi: From Classical to Molecular Methods

JM García-Martín, A Muro, P Fernández-Soto - Journal of Fungi, 2024 - mdpi.com
Human endemic mycoses are potentially fatal diseases caused by a diverse group of fungi
that can alter their morphology in response to an increase in temperature. These thermally …

Molecular characterization of siderophore biosynthesis in Paracoccidioides brasiliensis

MG Silva, JS De Curcio, MG Silva-Bailão, RM Lima… - IMA fungus, 2020 - Springer
Iron is an essential nutrient for all organisms. For pathogenic fungi, iron is essential for the
success of infection. Thus, these organisms have developed high affinity iron uptake …

Galectin-3 inhibits Paracoccidioides brasiliensis growth and impacts paracoccidioidomycosis through multiple mechanisms

O Hatanaka, CP Rezende, P Moreno… - MSphere, 2019 - Am Soc Microbiol
The thermodimorphic pathogenic fungi Paracoccidioides brasiliensis and Paracoccidioides
lutzii are the etiologic causes of paracoccidioidomycosis (PCM), the most prevalent systemic …

Updates in Paracoccidioides Biology and Genetic Advances in Fungus Manipulation

AFA Chaves, MV Navarro, YN de Barros, RS Silva… - Journal of Fungi, 2021 - mdpi.com
The dimorphic fungi of the Paracoccidioides genus are the causative agents of
paracoccidioidomycosis (PCM). This disease is endemic in Latin America and primarily …

Proteomic analysis of Paracoccidioides brasiliensis complex isolates: Correlation of the levels of differentially expressed proteins with in vivo virulence

CC do Amaral, GF Fernandes, AM Rodrigues… - PLoS …, 2019 - journals.plos.org
Background Paracoccidioidomycosis (PCM) is a systemic mycosis commonly found in Latin
America that is caused by distinct species of Paracoccidioides genus: Paracoccidioides …

Paracoccidioides lutzii Formamidase Contributes to Fungal Survival in Macrophages

LOHS Silva, TR Moreira, RA Gonçales, MV Tomazett… - Microorganisms, 2022 - mdpi.com
Nitrogen is a crucial nutrient for microorganisms that compose essential biomolecules.
However, hosts limit this nutrient as a strategy to counter infections, therefore, pathogens …

Molecular tagging of biocontrol fungus Trichoderma asperellum and its colonization in soil

HQ Xian, L Liu, YH Li, YN Yang… - Journal of applied …, 2020 - academic.oup.com
Aims To conduct molecular tagging of the biocontrol fungus Trichoderma asperellum strain
T4 and elucidate its colonization patterns in soil. Methods and Results We constructed an …

Interacting with Hemoglobin: Paracoccidioides spp. Recruits hsp30 on Its Cell Surface for Enhanced Ability to Use This Iron Source

AF de Souza, MV Tomazett, KS Freitas e Silva… - Journal of Fungi, 2021 - mdpi.com
Paracoccidioides spp. are thermally dimorphic fungi that cause paracoccidioidomycosis and
can affect both immunocompetent and immunocompromised individuals. The infection can …

Role of paracoccin on Paracoccidioides brasiliensis virulence and susceptibility to antifungal drugs in the Galleria mellonella larvae model

N de Souza Pitangui, FF Fernandes… - Virulence, 2023 - Taylor & Francis
Paracoccin (PCN), a Paracoccidioides brasiliensis glycoprotein, has been reported to play
roles in fungal biology and paracoccidioidomycosis pathogenesis. Lectin and chitinase …