Roles of plant retinoblastoma protein: cell cycle and beyond

B Desvoyes, C Gutierrez - The EMBO Journal, 2020 - embopress.org
The human retinoblastoma (RB 1) protein is a tumor suppressor that negatively regulates
cell cycle progression through its interaction with members of the E2F/DP family of …

Arabidopsis Retinoblastoma-related and Polycomb group proteins: cooperation during plant cell differentiation and development

A Kuwabara, W Gruissem - Journal of experimental botany, 2014 - academic.oup.com
RETINOBLASTOMA (RB) is a tumour suppressor gene originally discovered in patients that
develop eye tumours. The pRb protein is now well established as a key cell-cycle regulator …

Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR‐bound and RBR‐free complexes

Z Magyar, B Horvath, S Khan, B Mohammed… - The EMBO …, 2012 - embopress.org
Post‐embryonic growth in plants depends on the continuous supply of undifferentiated cells
within meristems. Proliferating cells maintain their competence for division by active …

Downregulation of multiple CDK inhibitor ICK/KRP genes upregulates the E2F pathway and increases cell proliferation, and organ and seed sizes in Arabidopsis

Y Cheng, L Cao, S Wang, Y Li, X Shi, H Liu… - The Plant …, 2013 - Wiley Online Library
The ICK/KRP cyclin‐dependent kinase (CDK) inhibitors are important plant cell cycle factors
sharing only limited similarity with the metazoan CIP/KIP family of CDK inhibitors. Little is …

E2FB interacts with RETINOBLASTOMA RELATED and regulates cell proliferation during leaf development

E Őszi, C Papdi, B Mohammed… - Plant …, 2020 - academic.oup.com
Cell cycle entry and quiescence are regulated by the E2F transcription factors in association
with RETINOBLASTOMA-RELATED (RBR). E2FB is considered to be a transcriptional …

Cell-cycle control as a target for calcium, hormonal and developmental signals: the role of phosphorylation in the retinoblastoma-centred pathway

D Dudits, E Ábrahám, P Miskolczi, F Ayaydin… - Annals of …, 2011 - academic.oup.com
Background During the life cycle of plants, both embryogenic and post-embryogenic growth
are essentially based on cell division and cell expansion that are under the control of …

Phosphorylation‐dependent regulation of plant chromatin and chromatin‐associated proteins

J Bigeard, N Rayapuram, D Pflieger, H Hirt - Proteomics, 2014 - Wiley Online Library
In eukaryotes, most of the DNA is located in the nucleus where it is organized with histone
proteins in a higher order structure as chromatin. Chromatin and chromatin‐associated …

RETINOBLASTOMA‐RELATED Has Both Canonical and Noncanonical Regulatory Functions During Thermo‐Morphogenic Responses in Arabidopsis Seedlings

RSB Hamid, F Nagy, N Kaszler… - Plant, Cell & …, 2024 - Wiley Online Library
Warm temperatures accelerate plant growth, but the underlying molecular mechanism is not
fully understood. Here, we show that increasing the temperature from 22° C to 28° C rapidly …

Beyond what your retina can see: similarities of retinoblastoma function between plants and animals, from developmental processes to epigenetic regulation

E Zluhan-Martínez, V Pérez-Koldenkova… - International journal of …, 2020 - mdpi.com
The Retinoblastoma protein (pRb) is a key cell cycle regulator conserved in a wide variety of
organisms. Experimental analysis of pRb's functions in animals and plants has revealed that …

Increasing phosphatidylinositol (4, 5) bisphosphate biosynthesis affects plant nuclear lipids and nuclear functions

CB Dieck, A Wood, I Brglez, M Rojas-Pierce… - Plant Physiology and …, 2012 - Elsevier
In order to characterize the effects of increasing phosphatidylinositol (4, 5) bisphosphate
(PtdIns (4, 5) P2) on nuclear function, we expressed the human phosphatidylinositol (4) …