DNA protection, molecular docking, enzyme inhibition and enzyme kinetic studies of 1,5,9-epideoxyloganic acid isolated from Nepeta aristata with bio-guided …

Y Başar, S Yenigün, Y İpek, L Behçet… - Journal of …, 2024 - Taylor & Francis
epideoxyloganic acid (ELA) was isolated from the aerial parts of endemic Nepeta aristata
Boiss Et Kotschy Ex Boiss crude extract (methanol: chloroform) using silica gel (hexane …

In vitro bioactivities and in silico enzyme interactions of abietatrien-3β-ol by bio-guided isolation from Nepeta italica subsp. italica

Y İpek, Y Başar, S Yenigün, L Behçet… - Journal of …, 2024 - Taylor & Francis
Abstract Abietatrien-3 β-ol (ATO) was isolated from the aerial part of the Nepeta italica
subsp. italica methanol-chloroform extract and studied antioxidant, enzyme inhibition, and …

Molecular docking, molecular dynamics, MM/PBSA approaches and bioactivity studies of nepetanudoside B isolated from endemic Nepeta aristata

Y Başar, İ Demirtaş, S Yenigün, Y İpek… - Journal of …, 2024 - Taylor & Francis
Nepetanudoside B (NNB) was isolated from aerial parts of endemic Nepeta aristata crude
extract (CH3OH-CHCl3) using silica gel (n-hexane, methanol, ethyl acetate, and …

Phytochemical profiling, molecular docking and ADMET prediction of crude extract of Atriplex nitens Schkuhr for the screening of antioxidant and urease inhibitory

Y Başar, S Yenigün, F Gül, T Ozen… - … Journal of Chemistry …, 2024 - dergipark.org.tr
Atriplex nitens Schkuhr (ANS), which grows naturally in arid and semi-arid regions of the
world, is highly resistant to drought and salty environments and is used as food and animal …

Isolation, characterization and evaluation of oxypeucedanin and osthol from local endemic Prangos aricakensis Behçet and Yapar root as antioxidant, enzyme …

SŞ Gökçimen, Y İpek, L Behçet… - Journal of …, 2024 - Taylor & Francis
Prangos species were previously used against many disorders due to their chemical
component. Prangos aricakensis Behçet & Yapar is a newly discovered local endemic …

Synthesis, spectral characterization and biological activities of o, o'-dihydroxyazo compounds containing gallic acid: Molecular docking and dynamics simulation and …

E Demir, H Kocaokutgen, S Yenigun, T Ozen - Journal of the Indian …, 2024 - Elsevier
In the investigation, diazonium derivatives of 2-aminophenol, 2-amino-4-methylphenol, 2-
amino-4-chlorophenol, and 2-amino-5-nitrophenol reacted with gallic acid to produce four …

Potential Pharmacological Properties of Triterpene Derivatives of Ursolic Acid

V Khwaza, BA Aderibigbe - Molecules, 2024 - pmc.ncbi.nlm.nih.gov
Ursolic acid (UA) and its derivatives have garnered significant attention due to their
extensive pharmacological activity. UA is a pentacyclic triterpenoid found in a variety of …

Phytochemical analysis of Silybum marianum flowers: Quantitative analysis of natural compounds and molecular docking application

Y Başar, R Erenler - Turkish Journal of Biodiversity, 2024 - turkbiod.artvin.edu.tr
Secondary metabolites in plants, identifying, quantifying, and determining the biological
activity of plants enables the use of plants in different fields such as pharmacology, food, and …

Phytochemical analysis of Robinia pseudoacacia flowers and leaf: quantitative analysis of natural compounds and molecular docking application

Y Başar, İ Hosaflıoğlu, R Erenler - Turkish Journal of …, 2024 - turkbiod.artvin.edu.tr
Phenolic compounds are widely found and well-known secondary metabolites in plants.
Identification, and quantification of phenolic compounds, and determination of their …

A potential DNA protector, enzyme inhibitor and in silico studies of daucosterol isolated from six Nepeta species

S Yenigun, Y Basar, Y Ipek, M Gok, L Behcet… - Process …, 2024 - Elsevier
Daucosterol (DAU) was isolated from the methanol-chloroform crude extract of six Nepeta
species (N. aristata, N. baytopii, N. italica, N. nuda albiflora, N. stenantha and N …